Vaccines based on the cell surface carbohydrates of pathogenic bacteria
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Academia Brasileira de Ciências
2005
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| _version_ | 1876473297369038848 |
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| author | Christopher Jones |
| author_facet | Christopher Jones |
| contents | Vaccines based on the cell surface carbohydrates of pathogenic bacteria Christopher Jones Multidisciplinaria (Ciencias Naturales y Exactas) lipopolysaccharides GlycoconjugateVaccines Capsularpolysaccharides Glycoconjugatevaccines,inwhichacellsurfacecarbohydratefromamicro-organismiscovalentlyattachedtoanappropriatecarrierproteinareprovingtobethemosteffectivemeanstogenerateprotectiveimmuneresponsestopreventawiderangeofdiseases.Thetechnologyappearstobegenericandapplicabletoawiderangeofpathogens,aslongasantibodiesagainstsurfacecarbohydrateshelpprotectagainstinfection.Threesuchvaccines,againstHaemophilusinfluenzaetypeb,NeisseriameningitidisGroupCandsevenserotypesofStreptococcuspneumoniae,havealreadybeenlicensedandmanyothersareindevelopment.Thisarticlediscussestherationaleforthedevelopmentanduseofglycoconjugatevaccines,themechanismsbywhichtheyelicitTcell-dependentimmuneresponsesandtheimplicationsofthisforvaccinedevelopment,theroleofphysicochemicalmethodsinthecharacterisationandqualitycontrolofthesevaccines,andthenovelproductswhichareunderdevelopment. 2005 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32777209 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.2 Vol.77 |
| format | Artículo científico |
| id | redalyc_32777209 |
| institution | Redalyc |
| language | en |
| publishDate | 2005 |
| publisher | Academia Brasileira de Ciências |
| spellingShingle | Vaccines based on the cell surface carbohydrates of pathogenic bacteria Christopher Jones Multidisciplinaria (Ciencias Naturales y Exactas) lipopolysaccharides GlycoconjugateVaccines Capsularpolysaccharides Vaccines based on the cell surface carbohydrates of pathogenic bacteria Christopher Jones Multidisciplinaria (Ciencias Naturales y Exactas) lipopolysaccharides GlycoconjugateVaccines Capsularpolysaccharides Glycoconjugatevaccines,inwhichacellsurfacecarbohydratefromamicro-organismiscovalentlyattachedtoanappropriatecarrierproteinareprovingtobethemosteffectivemeanstogenerateprotectiveimmuneresponsestopreventawiderangeofdiseases.Thetechnologyappearstobegenericandapplicabletoawiderangeofpathogens,aslongasantibodiesagainstsurfacecarbohydrateshelpprotectagainstinfection.Threesuchvaccines,againstHaemophilusinfluenzaetypeb,NeisseriameningitidisGroupCandsevenserotypesofStreptococcuspneumoniae,havealreadybeenlicensedandmanyothersareindevelopment.Thisarticlediscussestherationaleforthedevelopmentanduseofglycoconjugatevaccines,themechanismsbywhichtheyelicitTcell-dependentimmuneresponsesandtheimplicationsofthisforvaccinedevelopment,theroleofphysicochemicalmethodsinthecharacterisationandqualitycontrolofthesevaccines,andthenovelproductswhichareunderdevelopment. 2005 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32777209 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.2 Vol.77 |
| title | Vaccines based on the cell surface carbohydrates of pathogenic bacteria |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) lipopolysaccharides GlycoconjugateVaccines Capsularpolysaccharides |
| url | https://www.redalyc.org/articulo.oa?id=32777209 |