Time course of echocardiographic and electrocardiographic parameters in myocardial infarct in rats
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| Format: | Artículo científico |
| Langue: | en |
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Academia Brasileira de Ciências
2007
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| _version_ | 1876444227126165504 |
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| author | Amarildo Miranda |
| author_facet | Amarildo Miranda |
| contents | Time course of echocardiographic and electrocardiographic parameters in myocardial infarct in rats Amarildo Miranda Ricardo H. Costa-e-Sousa João P.S. Werneck-de-Castro Elisabete C. Mattos Vanessa P. Ribeiro Márcia G. Silva Regina C.S. Goldenberg Emerson L. Olivares Antônio Carlos Campos de Carvalho Multidisciplinaria (Ciencias Naturales y Exactas) rats infarct size echocardiogram electrocardiogram myocardial infarction In animal models the evaluation of myocardial infarct size in vivo and its relation to the actual lesion found post mortemis still a challenge. The purpose of the current study was to address if the conventional electrocardiogram (ECG)and/or echocardiogram (ECHO) could be used to adequately predict the size of the infarct in rats. Wistar rats wereinfarcted by left coronary ligation and then ECG, ECHO and histopathology were performed at 1, 7 and 28 days aftersurgery. Correlation between infarct size by histology and Q wave amplitude in lead L1 was only found when ECGswere performed one day post-surgery. Left ventricular diastolic and systolic dimensions correlated with infarct sizeby ECHO on day 7 post-infarction. On days 7 and 28 post-infarction, ejection indexes estimated by M-mode alsocorrelated with infarct size. In summary we show that conventional ECG and ECHO methods can be used to estimateinfarct size in rats. Our data suggest that the 7-day interval is actually the most accurate for estimation of infarct sizeby ECHO. 2007 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32779406 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.4 Vol.79 |
| format | Artículo científico |
| id | redalyc_32779406 |
| institution | Redalyc |
| language | en |
| publishDate | 2007 |
| publisher | Academia Brasileira de Ciências |
| spellingShingle | Time course of echocardiographic and electrocardiographic parameters in myocardial infarct in rats Amarildo Miranda Multidisciplinaria (Ciencias Naturales y Exactas) rats infarct size echocardiogram electrocardiogram myocardial infarction Time course of echocardiographic and electrocardiographic parameters in myocardial infarct in rats Amarildo Miranda Ricardo H. Costa-e-Sousa João P.S. Werneck-de-Castro Elisabete C. Mattos Vanessa P. Ribeiro Márcia G. Silva Regina C.S. Goldenberg Emerson L. Olivares Antônio Carlos Campos de Carvalho Multidisciplinaria (Ciencias Naturales y Exactas) rats infarct size echocardiogram electrocardiogram myocardial infarction In animal models the evaluation of myocardial infarct size in vivo and its relation to the actual lesion found post mortemis still a challenge. The purpose of the current study was to address if the conventional electrocardiogram (ECG)and/or echocardiogram (ECHO) could be used to adequately predict the size of the infarct in rats. Wistar rats wereinfarcted by left coronary ligation and then ECG, ECHO and histopathology were performed at 1, 7 and 28 days aftersurgery. Correlation between infarct size by histology and Q wave amplitude in lead L1 was only found when ECGswere performed one day post-surgery. Left ventricular diastolic and systolic dimensions correlated with infarct sizeby ECHO on day 7 post-infarction. On days 7 and 28 post-infarction, ejection indexes estimated by M-mode alsocorrelated with infarct size. In summary we show that conventional ECG and ECHO methods can be used to estimateinfarct size in rats. Our data suggest that the 7-day interval is actually the most accurate for estimation of infarct sizeby ECHO. 2007 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32779406 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.4 Vol.79 |
| title | Time course of echocardiographic and electrocardiographic parameters in myocardial infarct in rats |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) rats infarct size echocardiogram electrocardiogram myocardial infarction |
| url | https://www.redalyc.org/articulo.oa?id=32779406 |