Determinantes biopsicosociales de depresión en pacientes atendidos en Centros de Atención Primaria de Concepción, Chile
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| Format: | Artículo científico |
| Language: | es |
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Sociedad de Neurología, Psiquiatría y Neurocirugía de Chile
2016
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| _version_ | 1876429760524976128 |
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| author | Benjamín Vicente P. |
| author_facet | Benjamín Vicente P. |
| contents | Determinantes biopsicosociales de depresión en pacientes atendidos en Centros de Atención Primaria de Concepción, Chile Benjamín Vicente P. Romina Rojas P. Sandra Saldivia B. Cristhian Pérez V. Roberto Melipillán A. Nain Hormazábal P. Rolando Pihan V. Medicina Depression primary health care genetic predisposition to disease genes Risk factors associated to depression have been extensively studied, though there is a lack of prospective studies on factors that predict the incidence of depression in healthy people. There is not a predictive equation that incorporates genetic factors is not available. Method: A cohort study, prospective, with baseline assessments at 12 months was carried out on a random sample of attendees in primary care centers form the Concepción Province, Chile (n = 1,596). Eight psychosocial factors were measured and the genotyping of the uMAO and 5-HTTLPR in SLC6A4 as genetic factors polymorphisms was also carried out. The outcome variable was the presence/absence of depression at 12 months follow-up. A predictive model for depression was obtained by means of analyses of binary logistic regression. Results: Genetic variables have no statistically significant relation with the variable depression at 12 months follow up. Variables such as gender, educational level, satisfaction with living conditions, personal background of depression, self perception of both physical and mental health and satisfaction with relationship are related to the onset of depression in the follow up. Conclusions: Outcomes will allow identifying vulnerable people among the primary care attendees, who could participate in prevention programs. The study of further genes will be necessary in order to improve the predictive capacity of the model. 2016 artículo científico 0034-7388 https://www.redalyc.org/articulo.oa?id=331546792004 es http://www.redalyc.org/revista.oa?id=3315 Revista Chilena de Neuropsiquiatría application/pdf Sociedad de Neurología, Psiquiatría y Neurocirugía de Chile Revista Chilena de Neuropsiquiatría (Chile) Num.2 Vol.54 |
| format | Artículo científico |
| id | redalyc_331546792004 |
| institution | Redalyc |
| language | es |
| publishDate | 2016 |
| publisher | Sociedad de Neurología, Psiquiatría y Neurocirugía de Chile |
| spellingShingle | Determinantes biopsicosociales de depresión en pacientes atendidos en Centros de Atención Primaria de Concepción, Chile Benjamín Vicente P. Medicina Depression primary health care genetic predisposition to disease genes Determinantes biopsicosociales de depresión en pacientes atendidos en Centros de Atención Primaria de Concepción, Chile Benjamín Vicente P. Romina Rojas P. Sandra Saldivia B. Cristhian Pérez V. Roberto Melipillán A. Nain Hormazábal P. Rolando Pihan V. Medicina Depression primary health care genetic predisposition to disease genes Risk factors associated to depression have been extensively studied, though there is a lack of prospective studies on factors that predict the incidence of depression in healthy people. There is not a predictive equation that incorporates genetic factors is not available. Method: A cohort study, prospective, with baseline assessments at 12 months was carried out on a random sample of attendees in primary care centers form the Concepción Province, Chile (n = 1,596). Eight psychosocial factors were measured and the genotyping of the uMAO and 5-HTTLPR in SLC6A4 as genetic factors polymorphisms was also carried out. The outcome variable was the presence/absence of depression at 12 months follow-up. A predictive model for depression was obtained by means of analyses of binary logistic regression. Results: Genetic variables have no statistically significant relation with the variable depression at 12 months follow up. Variables such as gender, educational level, satisfaction with living conditions, personal background of depression, self perception of both physical and mental health and satisfaction with relationship are related to the onset of depression in the follow up. Conclusions: Outcomes will allow identifying vulnerable people among the primary care attendees, who could participate in prevention programs. The study of further genes will be necessary in order to improve the predictive capacity of the model. 2016 artículo científico 0034-7388 https://www.redalyc.org/articulo.oa?id=331546792004 es http://www.redalyc.org/revista.oa?id=3315 Revista Chilena de Neuropsiquiatría application/pdf Sociedad de Neurología, Psiquiatría y Neurocirugía de Chile Revista Chilena de Neuropsiquiatría (Chile) Num.2 Vol.54 |
| title | Determinantes biopsicosociales de depresión en pacientes atendidos en Centros de Atención Primaria de Concepción, Chile |
| topic | Medicina Depression primary health care genetic predisposition to disease genes |
| url | https://www.redalyc.org/articulo.oa?id=331546792004 |