Antioxidantes en poblaciones adultas del nivel del mar y de grandes alturas: Actividad de la superóxido dismutasa.
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| Format: | Artículo científico |
| Sprache: | es |
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Universidad Peruana Cayetano Heredia
2006
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| author | Segundo SECLÉN SANTISTEBAN |
| author_facet | Segundo SECLÉN SANTISTEBAN |
| contents | Antioxidantes en poblaciones adultas del nivel del mar y de grandes alturas: Actividad de la superóxido dismutasa. Segundo SECLÉN SANTISTEBAN Rossana BARACCO MAGGI Salim MOHANNA BARRENECHEA Medicina Peru Free radicals high altitude superoxide dismutase Free radicals constitute an important threat to the organism, in defense, cells have developed several antioxidant enzymes, superoxide dismutase (SOD), catalase and glutathione peroxidase. SOD is in charge of the removal of superoxide radicals produced in the mitochondrial electron transport chain. Objective: To determine and compare SOD levels of a high altitude and sea level population. Materials and Methods: This was a descriptive study. Blood samples were taken from blood donors of blood banks of Hospital Nacional Cayetano Heredia in Lima and Hospital Victor Ramos Guardia in Huaraz (3 052 meters above sea level). Ninety seven samples were analyzed using the Minami and Yoshikawa method to determine SOD activity. Results: The means for SOD values were 1 834 U/gr.Hb for Lima and 926.5 U/gr.Hb for Huaraz (p < 0.05). In every age group the high altitude natives had lower levels of SOD than the ones at sea level. There was a significant difference between women from Lima and Huaraz (1 929 U/gr.Hb vs. 941.89 U/gr.Hb; p < 0.05). The same was observed when comparing means of men from Lima and Huaraz (1 754 U/gr.Hb vs. 907.78 U/ gr.Hb; p < 0.05). Conclusions: High altitude natives have lower levels of SOD. 2006 artículo científico 1018-130X https://www.redalyc.org/articulo.oa?id=338029551002 es http://www.redalyc.org/revista.oa?id=3380 Revista Médica Herediana application/pdf Universidad Peruana Cayetano Heredia Revista Médica Herediana (Perú) Num.1 Vol.17 |
| format | Artículo científico |
| id | redalyc_338029551002 |
| institution | Redalyc |
| language | es |
| publishDate | 2006 |
| publisher | Universidad Peruana Cayetano Heredia |
| spellingShingle | Antioxidantes en poblaciones adultas del nivel del mar y de grandes alturas: Actividad de la superóxido dismutasa. Segundo SECLÉN SANTISTEBAN Medicina Peru Free radicals high altitude superoxide dismutase Antioxidantes en poblaciones adultas del nivel del mar y de grandes alturas: Actividad de la superóxido dismutasa. Segundo SECLÉN SANTISTEBAN Rossana BARACCO MAGGI Salim MOHANNA BARRENECHEA Medicina Peru Free radicals high altitude superoxide dismutase Free radicals constitute an important threat to the organism, in defense, cells have developed several antioxidant enzymes, superoxide dismutase (SOD), catalase and glutathione peroxidase. SOD is in charge of the removal of superoxide radicals produced in the mitochondrial electron transport chain. Objective: To determine and compare SOD levels of a high altitude and sea level population. Materials and Methods: This was a descriptive study. Blood samples were taken from blood donors of blood banks of Hospital Nacional Cayetano Heredia in Lima and Hospital Victor Ramos Guardia in Huaraz (3 052 meters above sea level). Ninety seven samples were analyzed using the Minami and Yoshikawa method to determine SOD activity. Results: The means for SOD values were 1 834 U/gr.Hb for Lima and 926.5 U/gr.Hb for Huaraz (p < 0.05). In every age group the high altitude natives had lower levels of SOD than the ones at sea level. There was a significant difference between women from Lima and Huaraz (1 929 U/gr.Hb vs. 941.89 U/gr.Hb; p < 0.05). The same was observed when comparing means of men from Lima and Huaraz (1 754 U/gr.Hb vs. 907.78 U/ gr.Hb; p < 0.05). Conclusions: High altitude natives have lower levels of SOD. 2006 artículo científico 1018-130X https://www.redalyc.org/articulo.oa?id=338029551002 es http://www.redalyc.org/revista.oa?id=3380 Revista Médica Herediana application/pdf Universidad Peruana Cayetano Heredia Revista Médica Herediana (Perú) Num.1 Vol.17 |
| title | Antioxidantes en poblaciones adultas del nivel del mar y de grandes alturas: Actividad de la superóxido dismutasa. |
| topic | Medicina Peru Free radicals high altitude superoxide dismutase |
| url | https://www.redalyc.org/articulo.oa?id=338029551002 |