Analysis of brief language tests in the detection of cognitive decline and dementia
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| Format: | Artículo científico |
| Langue: | en |
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Associação Neurologia Cognitiva e do Comportamento
2007
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| _version_ | 1876428348019703808 |
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| author | Marcia Radanovic |
| author_facet | Marcia Radanovic |
| contents | Analysis of brief language tests in the detection of cognitive decline and dementia Marcia Radanovic Maria Teresa Carthery-Goulart Helenice Charchat-Fichman Emílio Herrera Jr. Edson Erasmo Pereira Lima Jerusa Smid Cláudia Sellitto Porto Ricardo Nitrini Medicina dementia education Language tests Alzheimer disease cognitive disorders Lexical access difficulties are frequent in normal aging and initial stages of dementia. Verbal fluency tests are valuable to detect cognitive decline, evidencing lexico-semantic and executive dysfunction. Objectives: To establish which language tests can contribute in detecting dementia and to verify schooling influence on subject performance. Method: 74 subjects: 33 controls, 17 Clinical Dementia Rating (CDR) 0.5 and 24 (Brief Cognitive Battery - BCB e Boston Naming Test - BNT) 1 were compared in tests of semantic verbal fluency (animal and fruit), picture naming (BCB and BNT) and the language items of Mini Mental State Examination (MMSE). Results: There were significant differences between the control group and both CDR 0.5 and CDR 1 in all tests. Cut-off scores were: 11 and 10 for animal fluency, 8 for fruit fluency (in both), 8 and 9 for BCB naming. The CDR 0.5 group performed better than the CDR 1 group only in animal fluency. Stepwise multiple regression revealed fruit fluency,animal fluency and BCB naming as the best discriminators between patients and controls (specificity: 93.8%; sensitivity: 91.3%). In controls, comparison between illiterates and literates evidenced schooling influence in all tests, except for fruit fluency and BCB naming. In patients with dementia, only fruit fluency was uninfluenced by schooling. Conclusion: The combination of verbal fluency tests in two semantic categories along with a simple picturenaming test is highly sensitive in detecting cognitive decline. Comparison between literateand illiterate subjects shows a lesser degree of influence of schooling on the selected tests,thus improving discrimination between low performance and incipient cognitive decline. 2007 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339528997010 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.1 |
| format | Artículo científico |
| id | redalyc_339528997010 |
| institution | Redalyc |
| language | en |
| publishDate | 2007 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| spellingShingle | Analysis of brief language tests in the detection of cognitive decline and dementia Marcia Radanovic Medicina dementia education Language tests Alzheimer disease cognitive disorders Analysis of brief language tests in the detection of cognitive decline and dementia Marcia Radanovic Maria Teresa Carthery-Goulart Helenice Charchat-Fichman Emílio Herrera Jr. Edson Erasmo Pereira Lima Jerusa Smid Cláudia Sellitto Porto Ricardo Nitrini Medicina dementia education Language tests Alzheimer disease cognitive disorders Lexical access difficulties are frequent in normal aging and initial stages of dementia. Verbal fluency tests are valuable to detect cognitive decline, evidencing lexico-semantic and executive dysfunction. Objectives: To establish which language tests can contribute in detecting dementia and to verify schooling influence on subject performance. Method: 74 subjects: 33 controls, 17 Clinical Dementia Rating (CDR) 0.5 and 24 (Brief Cognitive Battery - BCB e Boston Naming Test - BNT) 1 were compared in tests of semantic verbal fluency (animal and fruit), picture naming (BCB and BNT) and the language items of Mini Mental State Examination (MMSE). Results: There were significant differences between the control group and both CDR 0.5 and CDR 1 in all tests. Cut-off scores were: 11 and 10 for animal fluency, 8 for fruit fluency (in both), 8 and 9 for BCB naming. The CDR 0.5 group performed better than the CDR 1 group only in animal fluency. Stepwise multiple regression revealed fruit fluency,animal fluency and BCB naming as the best discriminators between patients and controls (specificity: 93.8%; sensitivity: 91.3%). In controls, comparison between illiterates and literates evidenced schooling influence in all tests, except for fruit fluency and BCB naming. In patients with dementia, only fruit fluency was uninfluenced by schooling. Conclusion: The combination of verbal fluency tests in two semantic categories along with a simple picturenaming test is highly sensitive in detecting cognitive decline. Comparison between literateand illiterate subjects shows a lesser degree of influence of schooling on the selected tests,thus improving discrimination between low performance and incipient cognitive decline. 2007 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339528997010 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.1 |
| title | Analysis of brief language tests in the detection of cognitive decline and dementia |
| topic | Medicina dementia education Language tests Alzheimer disease cognitive disorders |
| url | https://www.redalyc.org/articulo.oa?id=339528997010 |