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| Format: | Artículo científico |
| Language: | en |
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Associação Neurologia Cognitiva e do Comportamento
2008
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| Online Access: | https://www.redalyc.org/articulo.oa?id=339529001002 |
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Table of Contents:
- Peripheral biomarkers of oxidative stress in aging and Alzheimer’s disease Tania Marcourakis Rosana Camarini Elisa Mitiko Kawamoto Leandro Rodrigues Scorsi Cristoforo Scavone Medicina aging aging oxidative stress oxidative stress Alzheimer’s disease Aging is associated with a greatly increased incidence of a number of neurodegenerative disorders, including Alzheimer’s disease (AD), Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS). These con-ditions are associated with chronic inflammation, which generates oxygen reactive species, ultimately responsible for a process known as oxidative stress. It is well established that this process is the culprit of neurodegeneration, and there are also mounting evidences that it is not restricted to the central nervous system. Indeed, several studies, including some by our group, have demonstrated that increased peripheral oxidative stress markers are associated to aging and, more specifically, to AD. Therefore, it is very instigating to regard aging and AD as systemic conditions that might be determined by studying peripheral markers of oxidative stress. 2008 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529001002 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.2