Neuropsychological rehabilitation program and behavioral disturbances in early-stage Alzheimer patients
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| Format: | Artículo científico |
| Language: | es |
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Associação Neurologia Cognitiva e do Comportamento
2008
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| _version_ | 1876488538013302784 |
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| author | Vera Lúcia Duarte Vieira |
| author_facet | Vera Lúcia Duarte Vieira |
| contents | Neuropsychological rehabilitation program and behavioral disturbances in early-stage Alzheimer patients Vera Lúcia Duarte Vieira Sônia Maria Dozzi Brucki Anna Luiza Costa Marques Martins Fabíola Canali Luciano Gois Vasconcelos Maira Okada de Oliveira Beatriz Schlecht Bittencourt Lúcia Julieta Tonato Leite Jacqueline Abrisqueta-Gomez Orlando Francisco Amodeo Bueno Medicina non dementia caregivers behavioral disorders pharmacological interventions Alzheimer’s disease (AD) is the most frequent cause of dementia and cholinesterase inhibitors are the available treatment in the mild stage. However cognitive rehabilitation has shown satisfactory results when combined with pharmacological treatment. Behavioral alteration is common in AD patients, which burdens caregivers and raises the risk of institutionalization. Providing caregivers guidance may enable them to assure better quality of life for patient and caregiver and lower institutionalization rates. Objective: To evaluate the effects of a neuropsycholog-ical rehabilitation program (NRP) combined with pharmacological treatment in early stage AD patients. Methods: We studied 12 AD patients (6 women), average age 75.42 (6.22) with 9.58 (5.6) years education in use of stable doses of cholinesterase inhibitors. Cognitive performance was evaluated using Mini-Mental State Examination (MMSE) and Alzheimer´s Disease Assessment Scale-cognitive (ADAS-Cog). Caregivers responded to Neuropsychi-atric Inventory (NPI) and Functional Activities Questionnaire (FAQ) at initial evaluation (T1), and after 8 months of rehabilitation program (T2). The program comprised two sessions every week and family guidance every fort-night. Results: MMSE (T1:23.25 (1.82)/T2:23.42 (2.81); ADAS-Cog (T1:17.11 (6.73)/T2:21.2 (8.59); NPI (T1:23.42 (23.38)/T2:19.83 (17.73); FAQ (T1:10.67 (7.24)/T2: 13.92 (6.92). Conclusions: These results show the importance of providing guidance and support for caretakers. Study limitations were the small number of patients and absence of a control group with only drug treatment to compare with combined pharmacological and rehabilitation treatments. 2008 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529002012 es http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.2 Vol.2 |
| format | Artículo científico |
| id | redalyc_339529002012 |
| institution | Redalyc |
| language | es |
| publishDate | 2008 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| spellingShingle | Neuropsychological rehabilitation program and behavioral disturbances in early-stage Alzheimer patients Vera Lúcia Duarte Vieira Medicina non dementia caregivers behavioral disorders pharmacological interventions Neuropsychological rehabilitation program and behavioral disturbances in early-stage Alzheimer patients Vera Lúcia Duarte Vieira Sônia Maria Dozzi Brucki Anna Luiza Costa Marques Martins Fabíola Canali Luciano Gois Vasconcelos Maira Okada de Oliveira Beatriz Schlecht Bittencourt Lúcia Julieta Tonato Leite Jacqueline Abrisqueta-Gomez Orlando Francisco Amodeo Bueno Medicina non dementia caregivers behavioral disorders pharmacological interventions Alzheimer’s disease (AD) is the most frequent cause of dementia and cholinesterase inhibitors are the available treatment in the mild stage. However cognitive rehabilitation has shown satisfactory results when combined with pharmacological treatment. Behavioral alteration is common in AD patients, which burdens caregivers and raises the risk of institutionalization. Providing caregivers guidance may enable them to assure better quality of life for patient and caregiver and lower institutionalization rates. Objective: To evaluate the effects of a neuropsycholog-ical rehabilitation program (NRP) combined with pharmacological treatment in early stage AD patients. Methods: We studied 12 AD patients (6 women), average age 75.42 (6.22) with 9.58 (5.6) years education in use of stable doses of cholinesterase inhibitors. Cognitive performance was evaluated using Mini-Mental State Examination (MMSE) and Alzheimer´s Disease Assessment Scale-cognitive (ADAS-Cog). Caregivers responded to Neuropsychi-atric Inventory (NPI) and Functional Activities Questionnaire (FAQ) at initial evaluation (T1), and after 8 months of rehabilitation program (T2). The program comprised two sessions every week and family guidance every fort-night. Results: MMSE (T1:23.25 (1.82)/T2:23.42 (2.81); ADAS-Cog (T1:17.11 (6.73)/T2:21.2 (8.59); NPI (T1:23.42 (23.38)/T2:19.83 (17.73); FAQ (T1:10.67 (7.24)/T2: 13.92 (6.92). Conclusions: These results show the importance of providing guidance and support for caretakers. Study limitations were the small number of patients and absence of a control group with only drug treatment to compare with combined pharmacological and rehabilitation treatments. 2008 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529002012 es http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.2 Vol.2 |
| title | Neuropsychological rehabilitation program and behavioral disturbances in early-stage Alzheimer patients |
| topic | Medicina non dementia caregivers behavioral disorders pharmacological interventions |
| url | https://www.redalyc.org/articulo.oa?id=339529002012 |