Cognitive impairment in Wilson’s disease
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| Format: | Artículo científico |
| Langue: | en |
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Associação Neurologia Cognitiva e do Comportamento
2009
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| _version_ | 1876428127656214528 |
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| author | Norberto Anizio Ferreira Frota |
| author_facet | Norberto Anizio Ferreira Frota |
| contents | Cognitive impairment in Wilson’s disease Norberto Anizio Ferreira Frota Paulo Caramelli Egberto Reis Barbosa Medicina dementia cognition Wilson’s disease Wilson`s disease (WD) or hepatolenticular degeneration is a rare, genetic and systemic disease, caused by a deficit in the metabolism of copper, leading to its accumulation in different organs, mainly the liver, followed by the central nervous system, especially the basal ganglia. When symptoms begin between the second and third decades of life, approximately 50% of the patients show neurological symptoms. Although dystonia and dysarthria are the most common neurological signs, cognitive changes have been reported since the first cases were described in 1912. Memory change is one of the most common impairments, but other cognitive changes have been reported, including dementia in untreated cases. In this article we review the cognitive changes in WD patients and the occurrence of dementia. 2009 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529012004 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.3 |
| format | Artículo científico |
| id | redalyc_339529012004 |
| institution | Redalyc |
| language | en |
| publishDate | 2009 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| spellingShingle | Cognitive impairment in Wilson’s disease Norberto Anizio Ferreira Frota Medicina dementia cognition Wilson’s disease Cognitive impairment in Wilson’s disease Norberto Anizio Ferreira Frota Paulo Caramelli Egberto Reis Barbosa Medicina dementia cognition Wilson’s disease Wilson`s disease (WD) or hepatolenticular degeneration is a rare, genetic and systemic disease, caused by a deficit in the metabolism of copper, leading to its accumulation in different organs, mainly the liver, followed by the central nervous system, especially the basal ganglia. When symptoms begin between the second and third decades of life, approximately 50% of the patients show neurological symptoms. Although dystonia and dysarthria are the most common neurological signs, cognitive changes have been reported since the first cases were described in 1912. Memory change is one of the most common impairments, but other cognitive changes have been reported, including dementia in untreated cases. In this article we review the cognitive changes in WD patients and the occurrence of dementia. 2009 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529012004 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.3 |
| title | Cognitive impairment in Wilson’s disease |
| topic | Medicina dementia cognition Wilson’s disease |
| url | https://www.redalyc.org/articulo.oa?id=339529012004 |