Dementia post-radiotherapy: improvement with acetylcholinesterase inhibitor. A case report

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Main Author: Antonio Eduardo Damin
Format: Artículo científico
Language:en
Published: Associação Neurologia Cognitiva e do Comportamento 2009
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author Antonio Eduardo Damin
author_facet Antonio Eduardo Damin
contents Dementia post-radiotherapy: improvement with acetylcholinesterase inhibitor. A case report Antonio Eduardo Damin Lílian S. Morillo Tíbor Rilho Perroco Wilson Jacob Filho Cássio Machado de Campos Bottino Medicina Dementia therapeutics radiotherapy cholinesterase inhibitors Cognitive decline associated with radiotherapy is a progressive complication that affects many patients submitted to this form of treatment. The lack of an effective treatment drives research for new treatment options to improve the quality of life of patients with this disorder. We report the case of a 64 year-old man who developed a severe dementia of the frontal subcortical type, which was associated with subcortical frontal lesions and appeared as a late complication of radiotherapy used to treat a pituitary tumor. After many pharmacological attempts to improve his cognitive and behavioral problems, the patient showed a significant improvement in the cognitive, functional and behavioral impairments after treatment with an acetylcholinesterase inhibitor. This report discusses hypotheses for the positive effect of this treatment. 2009 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529012013 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.3
format Artículo científico
id redalyc_339529012013
institution Redalyc
language en
publishDate 2009
publisher Associação Neurologia Cognitiva e do Comportamento
spellingShingle Dementia post-radiotherapy: improvement with acetylcholinesterase inhibitor. A case report
Antonio Eduardo Damin
Medicina
Dementia
therapeutics
radiotherapy
cholinesterase inhibitors
Dementia post-radiotherapy: improvement with acetylcholinesterase inhibitor. A case report Antonio Eduardo Damin Lílian S. Morillo Tíbor Rilho Perroco Wilson Jacob Filho Cássio Machado de Campos Bottino Medicina Dementia therapeutics radiotherapy cholinesterase inhibitors Cognitive decline associated with radiotherapy is a progressive complication that affects many patients submitted to this form of treatment. The lack of an effective treatment drives research for new treatment options to improve the quality of life of patients with this disorder. We report the case of a 64 year-old man who developed a severe dementia of the frontal subcortical type, which was associated with subcortical frontal lesions and appeared as a late complication of radiotherapy used to treat a pituitary tumor. After many pharmacological attempts to improve his cognitive and behavioral problems, the patient showed a significant improvement in the cognitive, functional and behavioral impairments after treatment with an acetylcholinesterase inhibitor. This report discusses hypotheses for the positive effect of this treatment. 2009 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529012013 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.3
title Dementia post-radiotherapy: improvement with acetylcholinesterase inhibitor. A case report
topic Medicina
Dementia
therapeutics
radiotherapy
cholinesterase inhibitors
url https://www.redalyc.org/articulo.oa?id=339529012013