Cognitive dysfunction in spinocerebellar ataxias
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| Format: | Artículo científico |
| Language: | en |
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Associação Neurologia Cognitiva e do Comportamento
2009
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| _version_ | 1876484951197614080 |
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| author | Helio Alfonso Ghizoni Teive |
| author_facet | Helio Alfonso Ghizoni Teive |
| contents | Cognitive dysfunction in spinocerebellar ataxias Helio Alfonso Ghizoni Teive Walter Oleschko Arruda Medicina dementia cognitive dysfunction spinocerebellar ataxia Spinocerebellar ataxias (SCAs) comprise a heterogeneous group of complex neurodegenerative diseases, characterized by the presence of progressive cerebellar ataxia, associated or otherwise with ophthalmoplegia, pyramidal signs, extrapyramidal features, pigmentary retinopathy, peripheral neuropathy, cognitive dysfunction and dementia. Objective: To verify the presence of cognitive dysfunction among the main types of SCA described in the literature. Methods: the review was conducted using the search system of the PUBMED and OMIM databases. Results: Cognitive dysfunction occurs in a considerable proportion of SCA, particularly in SCA 3, which is the most frequent form of SCA worldwide. Dementia has been described in several other types of SCA such as SCA 2, SCA 17 and DRPLA. Mental retardation is a specific clinical feature of SCA 13. Conclusions: The role of the cerebellum in cognitive functions has been observed in different types of SCAs which can manifest varying degrees of cognitive dysfunction, dementia and mental retardation. 2009 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529014002 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.3 Vol.3 |
| format | Artículo científico |
| id | redalyc_339529014002 |
| institution | Redalyc |
| language | en |
| publishDate | 2009 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| spellingShingle | Cognitive dysfunction in spinocerebellar ataxias Helio Alfonso Ghizoni Teive Medicina dementia cognitive dysfunction spinocerebellar ataxia Cognitive dysfunction in spinocerebellar ataxias Helio Alfonso Ghizoni Teive Walter Oleschko Arruda Medicina dementia cognitive dysfunction spinocerebellar ataxia Spinocerebellar ataxias (SCAs) comprise a heterogeneous group of complex neurodegenerative diseases, characterized by the presence of progressive cerebellar ataxia, associated or otherwise with ophthalmoplegia, pyramidal signs, extrapyramidal features, pigmentary retinopathy, peripheral neuropathy, cognitive dysfunction and dementia. Objective: To verify the presence of cognitive dysfunction among the main types of SCA described in the literature. Methods: the review was conducted using the search system of the PUBMED and OMIM databases. Results: Cognitive dysfunction occurs in a considerable proportion of SCA, particularly in SCA 3, which is the most frequent form of SCA worldwide. Dementia has been described in several other types of SCA such as SCA 2, SCA 17 and DRPLA. Mental retardation is a specific clinical feature of SCA 13. Conclusions: The role of the cerebellum in cognitive functions has been observed in different types of SCAs which can manifest varying degrees of cognitive dysfunction, dementia and mental retardation. 2009 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529014002 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.3 Vol.3 |
| title | Cognitive dysfunction in spinocerebellar ataxias |
| topic | Medicina dementia cognitive dysfunction spinocerebellar ataxia |
| url | https://www.redalyc.org/articulo.oa?id=339529014002 |