Diffusion tensor imaging for Alzheimer’s disease. A review of concepts and potential clinical applicability
Fuente:
Redalyc
Guardado en:
| Autor principal: | |
|---|---|
| Formato: | Artículo científico |
| Lenguaje: | en |
| Publicado: |
Associação Neurologia Cognitiva e do Comportamento
2009
|
| Materias: | |
| Acceso en línea: | |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| _version_ | 1876428790635167744 |
|---|---|
| author | Luciano de Gois Vasconcelos |
| author_facet | Luciano de Gois Vasconcelos |
| contents | Diffusion tensor imaging for Alzheimer’s disease. A review of concepts and potential clinical applicability Luciano de Gois Vasconcelos Sonia Maria Dozzi Brucki Andrea Parolin Jackowiski Orlando Francisco Amodeo Bueno Medicina review early diagnosis Alzheimer’s disease magnetic resonance imaging In view of the urgent need to identify an early and specific biomarker for Alzheimer`s disease (AD), a database search was performed using the terms "Alzheimer diasease" and "Diffusion Magnetic Resonance" Imaging” to enable review of Diffusion tensor imaging (DTI) concepts and its potential clinical role in AD evaluation. Detailed analysis of selected abstracts showed that the main DTI measures, fractional anisotropy and apparent diffusion coefficient, indicators of fiber tract integrity, provide a direct assessment of WM fibers and may be used as a new biomarker for AD. These findings were found to correlate with cognitive assessments, rates of AD progression and were also able to differentiate among groups including mild cognitive impairment, AD, and other dementias. Despite several consistent DTI findings in AD patients, there is still a lack of knowledge and studies on the DTI field. DTI is not yet ready for clinical use, and requires extensive further research in order to achieve this goal. 2009 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529015002 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.4 Vol.3 |
| format | Artículo científico |
| id | redalyc_339529015002 |
| institution | Redalyc |
| language | en |
| publishDate | 2009 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| spellingShingle | Diffusion tensor imaging for Alzheimer’s disease. A review of concepts and potential clinical applicability Luciano de Gois Vasconcelos Medicina review early diagnosis Alzheimer’s disease magnetic resonance imaging Diffusion tensor imaging for Alzheimer’s disease. A review of concepts and potential clinical applicability Luciano de Gois Vasconcelos Sonia Maria Dozzi Brucki Andrea Parolin Jackowiski Orlando Francisco Amodeo Bueno Medicina review early diagnosis Alzheimer’s disease magnetic resonance imaging In view of the urgent need to identify an early and specific biomarker for Alzheimer`s disease (AD), a database search was performed using the terms "Alzheimer diasease" and "Diffusion Magnetic Resonance" Imaging” to enable review of Diffusion tensor imaging (DTI) concepts and its potential clinical role in AD evaluation. Detailed analysis of selected abstracts showed that the main DTI measures, fractional anisotropy and apparent diffusion coefficient, indicators of fiber tract integrity, provide a direct assessment of WM fibers and may be used as a new biomarker for AD. These findings were found to correlate with cognitive assessments, rates of AD progression and were also able to differentiate among groups including mild cognitive impairment, AD, and other dementias. Despite several consistent DTI findings in AD patients, there is still a lack of knowledge and studies on the DTI field. DTI is not yet ready for clinical use, and requires extensive further research in order to achieve this goal. 2009 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529015002 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.4 Vol.3 |
| title | Diffusion tensor imaging for Alzheimer’s disease. A review of concepts and potential clinical applicability |
| topic | Medicina review early diagnosis Alzheimer’s disease magnetic resonance imaging |
| url | https://www.redalyc.org/articulo.oa?id=339529015002 |