Non-inflammatory cerebral amyloid angiopathy as a cause of rapidly progressive dementia. A case study
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| Format: | Artículo científico |
| Langue: | en |
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Associação Neurologia Cognitiva e do Comportamento
2009
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| _version_ | 1876479885572046848 |
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| author | Leonel Tadao Takada |
| author_facet | Leonel Tadao Takada |
| contents | Non-inflammatory cerebral amyloid angiopathy as a cause of rapidly progressive dementia. A case study Leonel Tadao Takada Paulo Camiz Lea T. Grinberg Claudia da Costa Leite Medicina Dementia vascular dementia cerebral amyloid angiopathy A 77 year-old men developed a subacute-onset, rapidly progressive cognitive decline. After 6 months of evolution, he scored 6 on the Mini-Mental State Examination and had left hemiparesis and hemineglect. The patient died 11 months after the onset of cognitive symptoms. Brain MRI showed microhemorrhages on gradient-echo sequence and confluent areas of white matter hyperintensities on T2-weighted images. Brain biopsy revealed amyloid-β peptide deposition in vessel walls, some of them surrounded by micro-bleeds. In this case report, we discuss the role of cerebral amyloid angiopathy (CAA) in cognitive decline, due to structural lesions associated with hemorrhages and infarcts, white matter lesions and co-morbidity of Alzheimer’s disease, as well as the most recently described amyloid angiopathy-related inflammation. 2009 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529015015 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.4 Vol.3 |
| format | Artículo científico |
| id | redalyc_339529015015 |
| institution | Redalyc |
| language | en |
| publishDate | 2009 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| spellingShingle | Non-inflammatory cerebral amyloid angiopathy as a cause of rapidly progressive dementia. A case study Leonel Tadao Takada Medicina Dementia vascular dementia cerebral amyloid angiopathy Non-inflammatory cerebral amyloid angiopathy as a cause of rapidly progressive dementia. A case study Leonel Tadao Takada Paulo Camiz Lea T. Grinberg Claudia da Costa Leite Medicina Dementia vascular dementia cerebral amyloid angiopathy A 77 year-old men developed a subacute-onset, rapidly progressive cognitive decline. After 6 months of evolution, he scored 6 on the Mini-Mental State Examination and had left hemiparesis and hemineglect. The patient died 11 months after the onset of cognitive symptoms. Brain MRI showed microhemorrhages on gradient-echo sequence and confluent areas of white matter hyperintensities on T2-weighted images. Brain biopsy revealed amyloid-β peptide deposition in vessel walls, some of them surrounded by micro-bleeds. In this case report, we discuss the role of cerebral amyloid angiopathy (CAA) in cognitive decline, due to structural lesions associated with hemorrhages and infarcts, white matter lesions and co-morbidity of Alzheimer’s disease, as well as the most recently described amyloid angiopathy-related inflammation. 2009 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529015015 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.4 Vol.3 |
| title | Non-inflammatory cerebral amyloid angiopathy as a cause of rapidly progressive dementia. A case study |
| topic | Medicina Dementia vascular dementia cerebral amyloid angiopathy |
| url | https://www.redalyc.org/articulo.oa?id=339529015015 |