Cognitive impairment in clinically isolated syndrome. A systematic review

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Autore principale: Carolina Fiorin Anhoque
Natura: Artículo científico
Lingua:en
Pubblicazione: Associação Neurologia Cognitiva e do Comportamento 2010
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author Carolina Fiorin Anhoque
author_facet Carolina Fiorin Anhoque
contents Cognitive impairment in clinically isolated syndrome. A systematic review Carolina Fiorin Anhoque Simone Cristina Aires Domingues Antônio Lúcio Teixeira Renan Barros Domingues Medicina Cognition cognitive impairment demyelinating disease clinically isolated syndrome The pattern of cognitive abnormalities in multiple sclerosis (MS) has been extensively studied and well characterized. However, little is known about the cognitive involvement in patients with the clinically isolated syndrome (CIS). Objectives: To perform a systematic review of the results of the studies on cognitive dysfunction in CIS patients. Methods: Cochrane, Lilacs, PubMed/Medline and SciELO databases were searched for studies involving patients with clinically isolated syndrome submitted to neuropsychological evaluation. Results: Seven studies fulfilled the selection criteria adopted in this review. The pattern of cognitive abnormalities in CIS resembles that found in patients with MS and is characterized by attention deficit, reduced information processing speed and impaired working memory and executive functions. The frequency of cognitive impairment in CIS seems to be lower than in MS. Conclusions: Cognition should be evaluated in patients with CIS. Future studies are required to evaluate the impact of cognitive abnormalities and to correlate them with axonal damage findings in patients with CIS. 2010 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529017002 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.2 Vol.4
format Artículo científico
id redalyc_339529017002
institution Redalyc
language en
publishDate 2010
publisher Associação Neurologia Cognitiva e do Comportamento
spellingShingle Cognitive impairment in clinically isolated syndrome. A systematic review
Carolina Fiorin Anhoque
Medicina
Cognition
cognitive impairment
demyelinating disease
clinically isolated syndrome
Cognitive impairment in clinically isolated syndrome. A systematic review Carolina Fiorin Anhoque Simone Cristina Aires Domingues Antônio Lúcio Teixeira Renan Barros Domingues Medicina Cognition cognitive impairment demyelinating disease clinically isolated syndrome The pattern of cognitive abnormalities in multiple sclerosis (MS) has been extensively studied and well characterized. However, little is known about the cognitive involvement in patients with the clinically isolated syndrome (CIS). Objectives: To perform a systematic review of the results of the studies on cognitive dysfunction in CIS patients. Methods: Cochrane, Lilacs, PubMed/Medline and SciELO databases were searched for studies involving patients with clinically isolated syndrome submitted to neuropsychological evaluation. Results: Seven studies fulfilled the selection criteria adopted in this review. The pattern of cognitive abnormalities in CIS resembles that found in patients with MS and is characterized by attention deficit, reduced information processing speed and impaired working memory and executive functions. The frequency of cognitive impairment in CIS seems to be lower than in MS. Conclusions: Cognition should be evaluated in patients with CIS. Future studies are required to evaluate the impact of cognitive abnormalities and to correlate them with axonal damage findings in patients with CIS. 2010 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529017002 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.2 Vol.4
title Cognitive impairment in clinically isolated syndrome. A systematic review
topic Medicina
Cognition
cognitive impairment
demyelinating disease
clinically isolated syndrome
url https://www.redalyc.org/articulo.oa?id=339529017002