Parkinson’s disease. Impact of clinical and cognitive aspects on quality of life
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| Format: | Artículo científico |
| Language: | en |
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Associação Neurologia Cognitiva e do Comportamento
2010
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| author | Glória Maria Almeida Souza Tedrus |
| author_facet | Glória Maria Almeida Souza Tedrus |
| contents | Parkinson’s disease. Impact of clinical and cognitive aspects on quality of life Glória Maria Almeida Souza Tedrus Lineu Correa Fonseca Patrícia Mencaroni Kange Medicina cognition depression quality of life Parkinson’s disease Parkinson’s disease (PD) is a chronic disease manifested principally by motor signs and symptoms, but with frequent neuropsychological alterations. Objectives: To study the relationship between clinical and cognitive aspects and the perception of quality of life (QOL) in PD patients. Methods: Twenty consecutive patients (13 men) with idiopathic PD (mean age: 64.5y), mean disease time of 7.8 years and at stages 1-3 according to the modified Hoehn and Yahr staging scale (HYS), all outpatients from the Neurology Department of the Celso Pierro General and Maternity Hospital (PUC-Campinas), were analyzed. The following were applied: a clinical-neurological assessment, the Mini-Mental State Examination (MMSE), standard neuropsychological battery of the CERAD (Consortium to Establish a Registry for Alzheimer’s Disease), Hamilton Depression Rating Scale (HAM-D) and a QOL questionnaire (Parkinson’s Disease Questionnaire - PDQ-39). Statistical analysis was carried out at a significance level of p<0.05. Results: On the PDQ-39 under the sections total, mobility and activities of daily living, and the items motor compromise (HYS) and language of the MMSE were predictors of worse QOL. Verbal fluency was a factor for emotional well-being on the PDQ-39, whereas higher scores for HAM-D and worse performance on the item attention and calculation of the MMSE were associated with worse QOL in the social support section. Total score on the MMSE and educational level were QOL factors in cognition . Conclusions: The findings of the present study suggest that clinical, cognitive, motor or other depression-related factors contribute differently to the domains of QOL. 2010 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529017010 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.2 Vol.4 |
| format | Artículo científico |
| id | redalyc_339529017010 |
| institution | Redalyc |
| language | en |
| publishDate | 2010 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| spellingShingle | Parkinson’s disease. Impact of clinical and cognitive aspects on quality of life Glória Maria Almeida Souza Tedrus Medicina cognition depression quality of life Parkinson’s disease Parkinson’s disease. Impact of clinical and cognitive aspects on quality of life Glória Maria Almeida Souza Tedrus Lineu Correa Fonseca Patrícia Mencaroni Kange Medicina cognition depression quality of life Parkinson’s disease Parkinson’s disease (PD) is a chronic disease manifested principally by motor signs and symptoms, but with frequent neuropsychological alterations. Objectives: To study the relationship between clinical and cognitive aspects and the perception of quality of life (QOL) in PD patients. Methods: Twenty consecutive patients (13 men) with idiopathic PD (mean age: 64.5y), mean disease time of 7.8 years and at stages 1-3 according to the modified Hoehn and Yahr staging scale (HYS), all outpatients from the Neurology Department of the Celso Pierro General and Maternity Hospital (PUC-Campinas), were analyzed. The following were applied: a clinical-neurological assessment, the Mini-Mental State Examination (MMSE), standard neuropsychological battery of the CERAD (Consortium to Establish a Registry for Alzheimer’s Disease), Hamilton Depression Rating Scale (HAM-D) and a QOL questionnaire (Parkinson’s Disease Questionnaire - PDQ-39). Statistical analysis was carried out at a significance level of p<0.05. Results: On the PDQ-39 under the sections total, mobility and activities of daily living, and the items motor compromise (HYS) and language of the MMSE were predictors of worse QOL. Verbal fluency was a factor for emotional well-being on the PDQ-39, whereas higher scores for HAM-D and worse performance on the item attention and calculation of the MMSE were associated with worse QOL in the social support section. Total score on the MMSE and educational level were QOL factors in cognition . Conclusions: The findings of the present study suggest that clinical, cognitive, motor or other depression-related factors contribute differently to the domains of QOL. 2010 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529017010 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.2 Vol.4 |
| title | Parkinson’s disease. Impact of clinical and cognitive aspects on quality of life |
| topic | Medicina cognition depression quality of life Parkinson’s disease |
| url | https://www.redalyc.org/articulo.oa?id=339529017010 |