Methodological issues and controversies in research on cognitive disorders
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| Format: | Artículo científico |
| Langue: | en |
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Associação Neurologia Cognitiva e do Comportamento
2010
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| _version_ | 1876478098039373824 |
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| author | Benito Pereira Damasceno |
| author_facet | Benito Pereira Damasceno |
| contents | Methodological issues and controversies in research on cognitive disorders Benito Pereira Damasceno Medicina epilepsy cognition double dissociation lesion localization neuropsychological tests Research on cognitive disorders is challenging due to the complexity of functions studied and to the numerous variables involved. First, the concept of cognition as a mediated (semiotic) and systemic activity is reviewed. According to this concept, the result of a local lesion is not an isolated symptom but a syndrome, and the best neuropsychological approach is an analysis based on appropriate tests to disclose double dissociations and thereby provide clues to brain-behavior relationships. This approach takes into account the influence of task-relevant variables (confounders) related to the patient (e.g., age, education), to the lesion (size, etiology), and to the tests and testing conditions (ecological validity, examiner’s experience), which need to be controlled and analyzed in multivariate statistical analyses, as illustrated in research on medial temporal lobe epilepsy. Other controversial issues such as single and double dissociations, single-case versus group studies, and the lesion method are also examined. 2010 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529019004 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.4 Vol.4 |
| format | Artículo científico |
| id | redalyc_339529019004 |
| institution | Redalyc |
| language | en |
| publishDate | 2010 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| spellingShingle | Methodological issues and controversies in research on cognitive disorders Benito Pereira Damasceno Medicina epilepsy cognition double dissociation lesion localization neuropsychological tests Methodological issues and controversies in research on cognitive disorders Benito Pereira Damasceno Medicina epilepsy cognition double dissociation lesion localization neuropsychological tests Research on cognitive disorders is challenging due to the complexity of functions studied and to the numerous variables involved. First, the concept of cognition as a mediated (semiotic) and systemic activity is reviewed. According to this concept, the result of a local lesion is not an isolated symptom but a syndrome, and the best neuropsychological approach is an analysis based on appropriate tests to disclose double dissociations and thereby provide clues to brain-behavior relationships. This approach takes into account the influence of task-relevant variables (confounders) related to the patient (e.g., age, education), to the lesion (size, etiology), and to the tests and testing conditions (ecological validity, examiner’s experience), which need to be controlled and analyzed in multivariate statistical analyses, as illustrated in research on medial temporal lobe epilepsy. Other controversial issues such as single and double dissociations, single-case versus group studies, and the lesion method are also examined. 2010 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529019004 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.4 Vol.4 |
| title | Methodological issues and controversies in research on cognitive disorders |
| topic | Medicina epilepsy cognition double dissociation lesion localization neuropsychological tests |
| url | https://www.redalyc.org/articulo.oa?id=339529019004 |