Effects of stress hormones on the brain and cognition. Evidence from normal to pathological aging
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| Format: | Artículo científico |
| Language: | en |
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Associação Neurologia Cognitiva e do Comportamento
2011
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| _version_ | 1876437536250789888 |
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| author | Juliana Nery de Souza-Talarico |
| author_facet | Juliana Nery de Souza-Talarico |
| contents | Effects of stress hormones on the brain and cognition. Evidence from normal to pathological aging Juliana Nery de Souza-Talarico Marie-France Marin Shireen Sindi Sonia J. Lupien Medicina aging memory Glucocorticoids Alzheimer’s disease Several studies have demonstrated a wide cognitive variability among aged individuals. One factor thought to be associated with this heterogeneity is exposure to chronic stress throughout life. Animal and human evidence demonstrates that glucocorticoids (GCs), the main class of stress hormones, are strongly linked to memory performance whereby elevated GC levels are associated with memory performance decline in both normal and pathological cognitive aging. Accordingly, it is believed that GCs may increase the brain’s vulnerability to the effects of internal and external insults, and thus may play a role in the development of age-related cognitive disorders such as Alzheimer’s disease (AD). The aim of this review article was to investigate the effects of GCs on normal and pathological cognitive aging by showing how these hormones interact with different brain structures involved in cognitive abilities, subsequently worsen memory performance, and increase the risk for developing dementia. 2011 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529026003 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.5 |
| format | Artículo científico |
| id | redalyc_339529026003 |
| institution | Redalyc |
| language | en |
| publishDate | 2011 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| spellingShingle | Effects of stress hormones on the brain and cognition. Evidence from normal to pathological aging Juliana Nery de Souza-Talarico Medicina aging memory Glucocorticoids Alzheimer’s disease Effects of stress hormones on the brain and cognition. Evidence from normal to pathological aging Juliana Nery de Souza-Talarico Marie-France Marin Shireen Sindi Sonia J. Lupien Medicina aging memory Glucocorticoids Alzheimer’s disease Several studies have demonstrated a wide cognitive variability among aged individuals. One factor thought to be associated with this heterogeneity is exposure to chronic stress throughout life. Animal and human evidence demonstrates that glucocorticoids (GCs), the main class of stress hormones, are strongly linked to memory performance whereby elevated GC levels are associated with memory performance decline in both normal and pathological cognitive aging. Accordingly, it is believed that GCs may increase the brain’s vulnerability to the effects of internal and external insults, and thus may play a role in the development of age-related cognitive disorders such as Alzheimer’s disease (AD). The aim of this review article was to investigate the effects of GCs on normal and pathological cognitive aging by showing how these hormones interact with different brain structures involved in cognitive abilities, subsequently worsen memory performance, and increase the risk for developing dementia. 2011 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529026003 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.5 |
| title | Effects of stress hormones on the brain and cognition. Evidence from normal to pathological aging |
| topic | Medicina aging memory Glucocorticoids Alzheimer’s disease |
| url | https://www.redalyc.org/articulo.oa?id=339529026003 |