Early and severe cognitive impairment in multiple sclerosis

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1. Verfasser: Maria Fernanda Mendes
Format: Artículo científico
Sprache:en
Veröffentlicht: Associação Neurologia Cognitiva e do Comportamento 2012
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author Maria Fernanda Mendes
author_facet Maria Fernanda Mendes
contents Early and severe cognitive impairment in multiple sclerosis Maria Fernanda Mendes Alessandro Finkelsztejn Sidney Gomes Yára Dadalti Fragoso Medicina dementia cognition basal ganglia brain atrophy Multiple sclerosis Objectives: To report on four new cases of severe cognitive impairment in the early stages of multiple sclerosis (MS) and to review data on the subject since few cases have been reported worldwide. Methods: Retrospective evaluation of medical records of patients with severe cognitive impairment within the first five years of MS diagnosis. Results on neuropsychological tests and magnetic resonance imaging (MRI) were disclosed. Results: Four patients from different Brazilian neurological departments in Brazil were evaluated, all presenting with severe cognitive dysfunction classified as rapidly developing dementia. MRI images showed severe brain atrophy and basal ganglia lesions in all patients. Conclusions: Although rare, severe cognitive impairment in MS represents an important disability and may ultimately constitute another form of the disease. 2012 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529036007 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.6
format Artículo científico
id redalyc_339529036007
institution Redalyc
language en
publishDate 2012
publisher Associação Neurologia Cognitiva e do Comportamento
spellingShingle Early and severe cognitive impairment in multiple sclerosis
Maria Fernanda Mendes
Medicina
dementia
cognition
basal ganglia
brain atrophy
Multiple sclerosis
Early and severe cognitive impairment in multiple sclerosis Maria Fernanda Mendes Alessandro Finkelsztejn Sidney Gomes Yára Dadalti Fragoso Medicina dementia cognition basal ganglia brain atrophy Multiple sclerosis Objectives: To report on four new cases of severe cognitive impairment in the early stages of multiple sclerosis (MS) and to review data on the subject since few cases have been reported worldwide. Methods: Retrospective evaluation of medical records of patients with severe cognitive impairment within the first five years of MS diagnosis. Results on neuropsychological tests and magnetic resonance imaging (MRI) were disclosed. Results: Four patients from different Brazilian neurological departments in Brazil were evaluated, all presenting with severe cognitive dysfunction classified as rapidly developing dementia. MRI images showed severe brain atrophy and basal ganglia lesions in all patients. Conclusions: Although rare, severe cognitive impairment in MS represents an important disability and may ultimately constitute another form of the disease. 2012 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529036007 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.6
title Early and severe cognitive impairment in multiple sclerosis
topic Medicina
dementia
cognition
basal ganglia
brain atrophy
Multiple sclerosis
url https://www.redalyc.org/articulo.oa?id=339529036007