Neuropathology of frontotemporal lobar degeneration. A review
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| Format: | Artículo científico |
| Language: | en |
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Associação Neurologia Cognitiva e do Comportamento
2013
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| _version_ | 1876479385699090432 |
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| author | Valéria Santoro Bahia |
| author_facet | Valéria Santoro Bahia |
| contents | Neuropathology of frontotemporal lobar degeneration. A review Valéria Santoro Bahia Leonel Tadao Takada Vincent Deramecourt Medicina TAU TDP FUS pathology frontotemporal lobar degeneration Frontotemporal lobar degenration (FTLD) is the second most common cause of presenile dementia. Threemain clinical variants are widely recognized within the FTLD spectrum: the behavioural variant of frontotemporal dementia (bvFTD), semantic dementia (SD) and progressive non-fluent aphasia (PNFA). FTLD represents a highly heterogeneous group of neurodegenerative disorders which are best classified according to the main protein component of pathological neuronal and glial inclusions. The most common pathological class of FTLD is associated with the TDP-43 protein (FTLD-TDP), while FTLD-Tau is considered slightly less common while the FTLD-FUS (Fused in sarcoma protein) pathology is rare. In this review, these three major pathological types of FTLD are discussed. 2013 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529042004 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.7 |
| format | Artículo científico |
| id | redalyc_339529042004 |
| institution | Redalyc |
| language | en |
| publishDate | 2013 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| spellingShingle | Neuropathology of frontotemporal lobar degeneration. A review Valéria Santoro Bahia Medicina TAU TDP FUS pathology frontotemporal lobar degeneration Neuropathology of frontotemporal lobar degeneration. A review Valéria Santoro Bahia Leonel Tadao Takada Vincent Deramecourt Medicina TAU TDP FUS pathology frontotemporal lobar degeneration Frontotemporal lobar degenration (FTLD) is the second most common cause of presenile dementia. Threemain clinical variants are widely recognized within the FTLD spectrum: the behavioural variant of frontotemporal dementia (bvFTD), semantic dementia (SD) and progressive non-fluent aphasia (PNFA). FTLD represents a highly heterogeneous group of neurodegenerative disorders which are best classified according to the main protein component of pathological neuronal and glial inclusions. The most common pathological class of FTLD is associated with the TDP-43 protein (FTLD-TDP), while FTLD-Tau is considered slightly less common while the FTLD-FUS (Fused in sarcoma protein) pathology is rare. In this review, these three major pathological types of FTLD are discussed. 2013 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529042004 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.7 |
| title | Neuropathology of frontotemporal lobar degeneration. A review |
| topic | Medicina TAU TDP FUS pathology frontotemporal lobar degeneration |
| url | https://www.redalyc.org/articulo.oa?id=339529042004 |