Functional profile of patients with behavioral variant frontotemporal dementia (bvFTD) compared to patients with Alzheimer’s disease and normal controls

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Main Author:	Thais Bento Lima-Silva
Format:	Artículo científico
Language:	en
Published:	Associação Neurologia Cognitiva e do Comportamento 2013
Subjects:	Medicina dependence functional status behavioral variant frontotemporal dementia
Online Access:	Acceder al recurso
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_version_	1876484505090392064
author	Thais Bento Lima-Silva
author_facet	Thais Bento Lima-Silva
contents	Functional profile of patients with behavioral variant frontotemporal dementia (bvFTD) compared to patients with Alzheimer’s disease and normal controls Thais Bento Lima-Silva Valéria Santoro Bahia Viviane Amaral Carvalho Henrique Cerqueira Guimarães Paulo Caramelli Márcio Balthazar Benito Damasceno Cássio Machado de Campos Bottino Sônia Maria Dozzi Brucki Ricardo Nitrini Mônica Sanches Yassuda Medicina dependence dependence functional status functional status behavioral variant frontotemporal dementia There are few studies describing the functional changes in behavioral variant frontotemporal dementia (bvFTD) and it is not clear which aspects of functionality are affected by the disease. Objective: The aim of the present investigation was to characterize the functional profile of patients previously diagnosed with bvFTD. Methods: The sample consisted of 31 patients diagnosed with bvFTD, who were compared to patients with Alzheimer’s disease (AD) (n=31) and to healthy control subjects (NC) (n=34), matched for schooling and age. bvFTD and AD patients were matched by severity of dementia. The protocol included the Mini-Mental State Examination (MMSE), Geriatric Depression Scale (GDS), Direct Assessment of Functional Status (DAFS-BR), Functional Activities Questionnaire (PFAQ), Disability Assessment for Dementia (DAD) and the Clinical Dementia Rating scale (CDR). Results: The group with bvFTD showed worse performance on Initiation and Planning/Organization in the DAD and on ability to feed oneself in the DAFS-BR, as well as higher scores on the PFAQ, suggesting greater dependence in the bvFTD group. Conclusion: The results suggest that individuals with bvFTD display greater functional impairment compared to AD patients with a similar degree of dementia severity and to healthy controls. Direct assessment of functionality proved unable to clearly differentiate between the dementia subtypes. 2013 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529042015 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.7
format	Artículo científico
id	redalyc_339529042015
institution	Redalyc
language	en
publishDate	2013
publisher	Associação Neurologia Cognitiva e do Comportamento
spellingShingle	Functional profile of patients with behavioral variant frontotemporal dementia (bvFTD) compared to patients with Alzheimer’s disease and normal controls Thais Bento Lima-Silva Medicina dependence dependence functional status functional status behavioral variant frontotemporal dementia Functional profile of patients with behavioral variant frontotemporal dementia (bvFTD) compared to patients with Alzheimer’s disease and normal controls Thais Bento Lima-Silva Valéria Santoro Bahia Viviane Amaral Carvalho Henrique Cerqueira Guimarães Paulo Caramelli Márcio Balthazar Benito Damasceno Cássio Machado de Campos Bottino Sônia Maria Dozzi Brucki Ricardo Nitrini Mônica Sanches Yassuda Medicina dependence dependence functional status functional status behavioral variant frontotemporal dementia There are few studies describing the functional changes in behavioral variant frontotemporal dementia (bvFTD) and it is not clear which aspects of functionality are affected by the disease. Objective: The aim of the present investigation was to characterize the functional profile of patients previously diagnosed with bvFTD. Methods: The sample consisted of 31 patients diagnosed with bvFTD, who were compared to patients with Alzheimer’s disease (AD) (n=31) and to healthy control subjects (NC) (n=34), matched for schooling and age. bvFTD and AD patients were matched by severity of dementia. The protocol included the Mini-Mental State Examination (MMSE), Geriatric Depression Scale (GDS), Direct Assessment of Functional Status (DAFS-BR), Functional Activities Questionnaire (PFAQ), Disability Assessment for Dementia (DAD) and the Clinical Dementia Rating scale (CDR). Results: The group with bvFTD showed worse performance on Initiation and Planning/Organization in the DAD and on ability to feed oneself in the DAFS-BR, as well as higher scores on the PFAQ, suggesting greater dependence in the bvFTD group. Conclusion: The results suggest that individuals with bvFTD display greater functional impairment compared to AD patients with a similar degree of dementia severity and to healthy controls. Direct assessment of functionality proved unable to clearly differentiate between the dementia subtypes. 2013 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339529042015 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.7
title	Functional profile of patients with behavioral variant frontotemporal dementia (bvFTD) compared to patients with Alzheimer’s disease and normal controls
topic	Medicina dependence dependence functional status functional status behavioral variant frontotemporal dementia
url	https://www.redalyc.org/articulo.oa?id=339529042015