Alzheimer and vascular brain disease: Senile dementia

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Main Author: Eliasz Engelhardt
Format: Artículo científico
Language:en
Published: Associação Neurologia Cognitiva e do Comportamento 2015
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author Eliasz Engelhardt
author_facet Eliasz Engelhardt
contents Alzheimer and vascular brain disease: Senile dementia Eliasz Engelhardt Lea T. Grinberg Medicina Alzheimer Senile dementia arteriosclerosis brain vascular disease Alois Alzheimer is best known for his description of a novel disease, subsequently named after him. However, his wide range of interests also included vascular brain diseases. He described Senile dementia, a highly heterogeneous condition, and was able not only to distinguish it from syphilitic brain disease, but also to discriminate two clinicopathological subtypes, that may be labeled a “arteriosclerotic subtype”, comparable to the present clinicopathological continuum of “Vascular cognitive impairment”, and another as a “neurodegenerative subtype”, characterized by primary [cortical] ganglion cell [nerve cells] degeneration, possibly foreshadowing a peculiar presenile disease that he was to describe some years later and would carry his name. He also considered the possibility of a senile presentation of this disease subtype, which was described by Oskar Fischer a short time later. Considering the clinicopathological overlapping features of the “arteriosclerotic subtype” of Senile dementia with Arteriosclerotic atrophy of the brain, it might be possible to consider that both represent a single condition. 2015 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339539880013 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.2 Vol.9
format Artículo científico
id redalyc_339539880013
institution Redalyc
language en
publishDate 2015
publisher Associação Neurologia Cognitiva e do Comportamento
spellingShingle Alzheimer and vascular brain disease: Senile dementia
Eliasz Engelhardt
Medicina
Alzheimer
Senile dementia
arteriosclerosis
brain vascular disease
Alzheimer and vascular brain disease: Senile dementia Eliasz Engelhardt Lea T. Grinberg Medicina Alzheimer Senile dementia arteriosclerosis brain vascular disease Alois Alzheimer is best known for his description of a novel disease, subsequently named after him. However, his wide range of interests also included vascular brain diseases. He described Senile dementia, a highly heterogeneous condition, and was able not only to distinguish it from syphilitic brain disease, but also to discriminate two clinicopathological subtypes, that may be labeled a “arteriosclerotic subtype”, comparable to the present clinicopathological continuum of “Vascular cognitive impairment”, and another as a “neurodegenerative subtype”, characterized by primary [cortical] ganglion cell [nerve cells] degeneration, possibly foreshadowing a peculiar presenile disease that he was to describe some years later and would carry his name. He also considered the possibility of a senile presentation of this disease subtype, which was described by Oskar Fischer a short time later. Considering the clinicopathological overlapping features of the “arteriosclerotic subtype” of Senile dementia with Arteriosclerotic atrophy of the brain, it might be possible to consider that both represent a single condition. 2015 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339539880013 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.2 Vol.9
title Alzheimer and vascular brain disease: Senile dementia
topic Medicina
Alzheimer
Senile dementia
arteriosclerosis
brain vascular disease
url https://www.redalyc.org/articulo.oa?id=339539880013