Risk factors for neurocognitive impairment in HIV-infected patients and comparison of different screening tools
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| Natura: | Artículo científico |
| Lingua: | en |
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Associação Neurologia Cognitiva e do Comportamento
2016
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| _version_ | 1876452058344718336 |
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| author | Elisa Moreira de Souza |
| author_facet | Elisa Moreira de Souza |
| contents | Risk factors for neurocognitive impairment in HIV-infected patients and comparison of different screening tools Elisa Moreira de Souza Caroline Schleiffer Buoniconti Frederico Cunha Valim Alexandre Sampaio Moura Medicina HIV Mini dementia Mental State Examination International HIV Dementia Scale HIV-associated neurocognitive disorder (HAND) is relatively frequent among HIV-infected patients and is often underdiagnosed. Assessment of HAND in daily clinical practice is challenging and different tools have been proposed. Objective: To evaluate risk factors and compare different screening tools for neurocognitive impairment in HIV-infected patients. Methods: HIV-infected patients were evaluated using the International HIV-Dementia Scale (IHDS), Mini-Mental State Examination (MMSE) and a neurocognitive self-perception questionnaire recommended by the European AIDS Clinical Society. Sociodemographic, clinical and laboratory data were obtained through chart review and patient interview. Results: Among the 63 patients included, low performance on the IHDS was observed in 54.0% and IHDS score was inversely associated with age (OR 0.13; 95%CI [0.02–0.67]). Regarding cognitive self-perception, 63.5% of patients reported no impairment on the three domains covered by the questionnaire. Among those patients self-reporting no problems, 42.1% had low performance on the IHDS. None of the patients scored below the education-adjusted cut-off on the MMSE. Conclusion: IHDS scores suggestive of HAND were observed in more than half of the patients and lower scores were found among older patients. There was low agreement between the different tools, suggesting that the MMSE may be inadequate for assessing HAND. The self-assessment questionnaire had low sensitivity and might not be useful as a screening tool. 2016 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339544714008 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.10 |
| format | Artículo científico |
| id | redalyc_339544714008 |
| institution | Redalyc |
| language | en |
| publishDate | 2016 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| spellingShingle | Risk factors for neurocognitive impairment in HIV-infected patients and comparison of different screening tools Elisa Moreira de Souza Medicina HIV Mini dementia Mental State Examination International HIV Dementia Scale Risk factors for neurocognitive impairment in HIV-infected patients and comparison of different screening tools Elisa Moreira de Souza Caroline Schleiffer Buoniconti Frederico Cunha Valim Alexandre Sampaio Moura Medicina HIV Mini dementia Mental State Examination International HIV Dementia Scale HIV-associated neurocognitive disorder (HAND) is relatively frequent among HIV-infected patients and is often underdiagnosed. Assessment of HAND in daily clinical practice is challenging and different tools have been proposed. Objective: To evaluate risk factors and compare different screening tools for neurocognitive impairment in HIV-infected patients. Methods: HIV-infected patients were evaluated using the International HIV-Dementia Scale (IHDS), Mini-Mental State Examination (MMSE) and a neurocognitive self-perception questionnaire recommended by the European AIDS Clinical Society. Sociodemographic, clinical and laboratory data were obtained through chart review and patient interview. Results: Among the 63 patients included, low performance on the IHDS was observed in 54.0% and IHDS score was inversely associated with age (OR 0.13; 95%CI [0.02–0.67]). Regarding cognitive self-perception, 63.5% of patients reported no impairment on the three domains covered by the questionnaire. Among those patients self-reporting no problems, 42.1% had low performance on the IHDS. None of the patients scored below the education-adjusted cut-off on the MMSE. Conclusion: IHDS scores suggestive of HAND were observed in more than half of the patients and lower scores were found among older patients. There was low agreement between the different tools, suggesting that the MMSE may be inadequate for assessing HAND. The self-assessment questionnaire had low sensitivity and might not be useful as a screening tool. 2016 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339544714008 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.1 Vol.10 |
| title | Risk factors for neurocognitive impairment in HIV-infected patients and comparison of different screening tools |
| topic | Medicina HIV Mini dementia Mental State Examination International HIV Dementia Scale |
| url | https://www.redalyc.org/articulo.oa?id=339544714008 |