Cognitive impairment in Spinocerebellar ataxia type 10
Fuente:
Redalyc
Guardado en:
| Autor principal: | |
|---|---|
| Formato: | Artículo científico |
| Lenguaje: | en |
| Publicado: |
Associação Neurologia Cognitiva e do Comportamento
2016
|
| Materias: | |
| Acceso en línea: | |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| _version_ | 1876487227061567488 |
|---|---|
| author | Adriana Moro |
| author_facet | Adriana Moro |
| contents | Cognitive impairment in Spinocerebellar ataxia type 10 Adriana Moro Hélio Afonso Ghizoni Teive Medicina psychiatric neuropsychological cognitive dysfunction Spinocerebellar ataxia type 10 Background: Cognitive and psychiatric dysfunction has been described in several neurodegenerative diseases but has not been systematically evaluated in spinocerebellar ataxia type 10 (SCA10). Objective: The aim of the present study was to investigate the core cognitive features in a large cohort of Brazilian patients with SCA10, comparing the results against a healthy control group. Methods: Twenty-eight SCA10 and 28 healthy subjects were prospectively assessed regarding cognitive function and psychiatric disorders at the Movement Disorders Unit of the Federal University of Paraná between February 2012 and October 2014. Results: The SCA10 group had worse depression scores, as well as cognitive performance, when compared to healthy individuals. Conclusion: Our study showed mild cognitive and mood dysfunctions in patients with SCA10, consistent with the symptoms reported in the Cerebellar Cognitive Affective Syndrome described by Schmahmann JD in 1998. The description of these findings is an important clinical phenomenon that may guide physicians in specific disease management and improve quality of life of these patients. 2016 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339548909010 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.4 Vol.10 |
| format | Artículo científico |
| id | redalyc_339548909010 |
| institution | Redalyc |
| language | en |
| publishDate | 2016 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| spellingShingle | Cognitive impairment in Spinocerebellar ataxia type 10 Adriana Moro Medicina psychiatric neuropsychological cognitive dysfunction Spinocerebellar ataxia type 10 Cognitive impairment in Spinocerebellar ataxia type 10 Adriana Moro Hélio Afonso Ghizoni Teive Medicina psychiatric neuropsychological cognitive dysfunction Spinocerebellar ataxia type 10 Background: Cognitive and psychiatric dysfunction has been described in several neurodegenerative diseases but has not been systematically evaluated in spinocerebellar ataxia type 10 (SCA10). Objective: The aim of the present study was to investigate the core cognitive features in a large cohort of Brazilian patients with SCA10, comparing the results against a healthy control group. Methods: Twenty-eight SCA10 and 28 healthy subjects were prospectively assessed regarding cognitive function and psychiatric disorders at the Movement Disorders Unit of the Federal University of Paraná between February 2012 and October 2014. Results: The SCA10 group had worse depression scores, as well as cognitive performance, when compared to healthy individuals. Conclusion: Our study showed mild cognitive and mood dysfunctions in patients with SCA10, consistent with the symptoms reported in the Cerebellar Cognitive Affective Syndrome described by Schmahmann JD in 1998. The description of these findings is an important clinical phenomenon that may guide physicians in specific disease management and improve quality of life of these patients. 2016 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339548909010 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.4 Vol.10 |
| title | Cognitive impairment in Spinocerebellar ataxia type 10 |
| topic | Medicina psychiatric neuropsychological cognitive dysfunction Spinocerebellar ataxia type 10 |
| url | https://www.redalyc.org/articulo.oa?id=339548909010 |