Neuroimaging in cerebral small vessel disease. Update and new concepts

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1. Verfasser: Mika Shibuya
Format: Artículo científico
Sprache:en
Veröffentlicht: Associação Neurologia Cognitiva e do Comportamento 2017
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author Mika Shibuya
author_facet Mika Shibuya
contents Neuroimaging in cerebral small vessel disease. Update and new concepts Mika Shibuya Claudia da Costa Leite Leandro Tavares Lucato Medicina Neuroimaging magnetic resonance small vessel disease In recent years, small vessel disease (SVD) has been recognized for its major impact on cognitive impairment in elderly people, where it is often difficult to separate its effects from those of neurodegenerative diseases individually. SVD is a systemic disease, probably related to diffuse endothelial dysfunction, which affects the perforating arterioles, capillaries and venules in the brain. Although often asymptomatic, it is responsible for almost half of all dementia cases and a significant proportion of stroke cases. Imaging features found on magnetic resonance include recent small subcortical infarctions, lacunes of presumed vascular origin, white matter hyperintensity of presumed vascular origin, prominent perivascular spaces and cerebral microbleeds. The recognition of these imaging findings as a spectrum of the same disease caused by endothelial dysfunction of small cerebral vessels can allow an overall analysis of the disease and thus the development of more effective preventive and therapeutic strategies. 2017 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339554592002 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.4 Vol.11
format Artículo científico
id redalyc_339554592002
language en
publishDate 2017
publisher Associação Neurologia Cognitiva e do Comportamento
spellingShingle Neuroimaging in cerebral small vessel disease. Update and new concepts
Mika Shibuya
Medicina
Neuroimaging
magnetic resonance
small vessel disease
Neuroimaging in cerebral small vessel disease. Update and new concepts Mika Shibuya Claudia da Costa Leite Leandro Tavares Lucato Medicina Neuroimaging magnetic resonance small vessel disease In recent years, small vessel disease (SVD) has been recognized for its major impact on cognitive impairment in elderly people, where it is often difficult to separate its effects from those of neurodegenerative diseases individually. SVD is a systemic disease, probably related to diffuse endothelial dysfunction, which affects the perforating arterioles, capillaries and venules in the brain. Although often asymptomatic, it is responsible for almost half of all dementia cases and a significant proportion of stroke cases. Imaging features found on magnetic resonance include recent small subcortical infarctions, lacunes of presumed vascular origin, white matter hyperintensity of presumed vascular origin, prominent perivascular spaces and cerebral microbleeds. The recognition of these imaging findings as a spectrum of the same disease caused by endothelial dysfunction of small cerebral vessels can allow an overall analysis of the disease and thus the development of more effective preventive and therapeutic strategies. 2017 artículo científico 1980-5764 https://www.redalyc.org/articulo.oa?id=339554592002 en http://www.redalyc.org/revista.oa?id=3395 Dementia & Neuropsychologia application/pdf Associação Neurologia Cognitiva e do Comportamento Dementia & Neuropsychologia (Brasil) Num.4 Vol.11
title Neuroimaging in cerebral small vessel disease. Update and new concepts
topic Medicina
Neuroimaging
magnetic resonance
small vessel disease
url https://www.redalyc.org/articulo.oa?id=339554592002