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Autor principal:	Xiomara Yáñez-Rueda
Formato:	Artículo científico
Lenguaje:	es
Publicado:	Universidad Industrial de Santander 2009
Materias:	Medicina Myrtaceae Candida spp citotoxicidad Aspergillus spp actividad antiviral
Acceso en línea:	https://www.redalyc.org/articulo.oa?id=343835696008
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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Composición química y actividad biológica de aceites esenciales de Calycolpus moritzianus recolectado en el Norte de Santander, Colombia Xiomara Yáñez-Rueda Liliana Betancur-Galvis Lee Solbay Agudelo-Gómez Maria Bibiana Zapata Julieth Correa-Royero Ana Cecilia Mesa-Arango Elena Stashenko Medicina Myrtaceae Candida spp citotoxicidad Aspergillus spp actividad antiviral Introducción : Actualmente, se están llevando a cabo estudios sobre la actividad biológica de AEs de plantas de la familia Myrtaceae. El objetivo de esta investigación fue la caracterización química y la evaluación de la actividad antimicótica, antitumoral y antiviral de 40 aceites extraídos de plantas de la especie Calycolpus moritzianus, comúnmente llamada “arrayán ó cínaro”, recolectadas en varias zonas del Norte de Santander, Colombia. Materiales y métodos : la actividad antimicótica se evaluó contra: Candida krusei , C. parapsilosis , Aspergillus fumigatus y A. flavus, siguiendo las técnicas estándar EUCAST y CLSI M38-A, respectivamente, para levaduras y hongos filamentosos. La citotoxicidad se evaluó en las líneas celulares tumorales (HeLa, Jurkat) y no tumorales (Vero) mediante la técnica fotocolorimétrica del MTT. La actividad antiviral in vitro, contra el virus Herpes simplex tipo 1 (HSV-1), se realizó mediante la “técnica de titulación del punto final (EPTT)”. Resultados y Discusión: los aceites X38 y X39, de muestras recolectadas en los municipios de Chinácota y Salazar, mostraron actividad contra C. krusei con valores de concentraciones inhibitorias mínimas de 500 μg/mL. Ninguno de los aceites fue citotóxico en células no tumorales Vero. Los aceites X9 y X10, procedentes de los municipios de Salazar y Pamplonita, fueron los más citotóxicos sobre células HeLa, a concentraciones de 37,8 ± 2,4 y 40,6 ± 2,6 μg/mL, respectivamente. La reducción de la carga viral en los cultivos celulares sólo fue lograda por el aceite X11. La actividad antimicótica y antitumoral de los aceites fue correlacionada con la composición de los componentes mayoritarios, evidenciándose la actividad del Terpinen-4-ol, (-) Limoneno, α-Pineno y Linalol. 2009 artículo científico 0121-0807 https://www.redalyc.org/articulo.oa?id=343835696008 es http://www.redalyc.org/revista.oa?id=3438 Revista de la Universidad Industrial de Santander. Salud application/pdf Universidad Industrial de Santander Revista de la Universidad Industrial de Santander. Salud (Colombia) Num.3 Vol.41

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// Anecdotal testing Today and Yesterday seems to indicate destroy() // is called by the garbage collector and everything is good. // Something to keep in mind though. return 0; } /** * Write function that is called when session data is to be saved. * * @param string $sessId The current session ID * @param string $data The session data to write * * @return bool */ public function write($sessId, $data): bool { if ($this->writesDisabled) { return true; } return $this->saveSession($sessId, $data); } /** * A function that is called internally when session data is to be saved. * * @param string $sessId The current session ID * @param string $data The session data to write * * @return bool */ abstract protected function saveSession($sessId, $data): bool; }

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