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| Format: | Artículo científico |
| Language: | en |
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Universidad Nacional Autónoma de México
2021
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| Online Access: | https://www.redalyc.org/articulo.oa?id=358971690001 https://www.redalyc.org/journal/3589/358971690001/ https://www.redalyc.org/journal/3589/358971690001/html/ https://www.redalyc.org/journal/3589/358971690001/358971690001.epub https://www.redalyc.org/journal/3589/358971690001/movil |
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Table of Contents:
- Food Craving in Obese Subjects: Its Correlation with Atherogenic Index and Feeding Behavior-Related Gene Expression Nadia Mabel Pérez-Vielma Ángel Miliar-García Modesto Gómez-López María Delfina Marín Soto Gerardo Leija-Alva Víctor Ricardo Aguilera Sosa Psicología Food craving Expresión génica Índice aterogénico Lípidos sanguíneos Estudio observacional descriptivo Obesity is influenced by environmental, behavioral, and genetic factors; particularly genes related to the regulation of lipids and addictive behavior. Food craving (FC) is a physiological and behavioral response that triggers the intense desire to ingest food, particularly food with high energy, fat, and/or sweet content. Objective: To evaluate the relationship between the prevalence of FC in obese subjects and blood lipids as well as to determine the transcriptional modulation of CART, DRD2, and FTO. Method: Transverse, comparative, and randomized study including 21 obese participants (BMI, ≥ 30 kg/m2 and 20 normal weight participants (BMI, ≤ 25 kg/m2). We determined CART, DRD2, and FTO expressions; evaluated blood lipid levels; and obtained trait scores on the Food Craving Questionnaire-Trait, a multifactorial instrument validated for the Mexican population. Results: The DRD2 expression was significantly increased (p = 0.027) and the CART expression was significantly decreased (p = 0.001) in obese participants compared with normal weight participants. The FTO expression did not show significant differences. Food Craving Questionnaire-Trait showed scores of ≥ 72 in obese participants. Conclusions: Linear regression model analysis showed that FC is a predictor of atherogenic index (ATH), independently of BMI, and of the gene expression modulation of CART and DRD2. 2021 artículo científico 2007-4832 https://www.redalyc.org/articulo.oa?id=358971690001 https://www.redalyc.org/journal/3589/358971690001/ https://www.redalyc.org/journal/3589/358971690001/html/ https://www.redalyc.org/journal/3589/358971690001/358971690001.epub https://www.redalyc.org/journal/3589/358971690001/movil 10.22201/fpsi.20074719e.2021.3.388 en http://www.redalyc.org/revista.oa?id=3589 Acta de Investigación Psicológica - Psychological Research Records application/pdf Universidad Nacional Autónoma de México Acta de Investigación Psicológica - Psychological Research Records (México) Num.3 Vol.11