Antifungal capacity of aqueous extracts of ilex paraguariensis fruits against dermatophite fungi
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Universidad Nacional de Misiones
2023
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| _version_ | 1876478776369479680 |
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| author | Beda E. Mereles Rodríguez |
| author_facet | Beda E. Mereles Rodríguez |
| contents | Antifungal capacity of aqueous extracts of ilex paraguariensis fruits against dermatophite fungi Beda E. Mereles Rodríguez Jacqueline N. Fiedler Miriam E. Chade Geología Dermatophytes yerba mate fruits antifungal activity Increasing resistance to antifungal agents and the toxicity of currently available antifungal agents has stimulated the development of new compounds with antifungal action of natural origin. Numerous scientific studies have reported on the biomedical and pharmacological properties of the de-rivatives of Ilex paraguariensis (Yerba mate). Very few scientific studies have been conducted on the phytochemical and/or pharmacological properties of its fruits, and practically none on its antimicrobial capacity. The aim of this study was to evaluate the in vitro antifungal capacity of aqueous extracts of I. paraguariensis fruits on dermatophyte fungi.Strains isolated from clinical samples of Trichophyton men-tagrophytes complex, Trichophyton rubrum, Microsporumcanis, Trichophyton tonsurans and Nannizziagypsea were used. To evaluate the antifungal capacity of the aqueous extract of yerba mate (EAFYM), a stock solution of 500 mg/ml was prepared. The quantitative microdilution method was applied in RPMI broth. A fungal inoculum of 1-3 x103 CFU/ml was used. Controls for fungal growth, sterility and commercial reference antifungals were performed. Cultures were incubated for 96 h at 35 °C. The minimum concentration of EAFYM that produced complete inhibition of fungal growth was determined by visual observation and subsequent puncture on solid medium. It is concluded that EAFYM has in vitro antifungal activity against the dermatophyte strains studied, ranging from 31.25 to 125 mg/ml. 2023 artículo científico 0329-8922 https://www.redalyc.org/articulo.oa?id=382679663003 https://www.redalyc.org/journal/3826/382679663003/ https://www.redalyc.org/journal/3826/382679663003/html/ https://www.redalyc.org/journal/3826/382679663003/382679663003.epub https://www.redalyc.org/journal/3826/382679663003/movil 10.36995/j.recyt.2023.39.003 en http://www.redalyc.org/revista.oa?id=3826 Revista de Ciencia y Tecnología application/pdf Universidad Nacional de Misiones Revista de Ciencia y Tecnología (Argentina) Num.1 Vol.39 |
| format | Artículo científico |
| id | redalyc_382679663003 |
| institution | Redalyc |
| language | en |
| publishDate | 2023 |
| publisher | Universidad Nacional de Misiones |
| spellingShingle | Antifungal capacity of aqueous extracts of ilex paraguariensis fruits against dermatophite fungi Beda E. Mereles Rodríguez Geología Dermatophytes yerba mate fruits antifungal activity Antifungal capacity of aqueous extracts of ilex paraguariensis fruits against dermatophite fungi Beda E. Mereles Rodríguez Jacqueline N. Fiedler Miriam E. Chade Geología Dermatophytes yerba mate fruits antifungal activity Increasing resistance to antifungal agents and the toxicity of currently available antifungal agents has stimulated the development of new compounds with antifungal action of natural origin. Numerous scientific studies have reported on the biomedical and pharmacological properties of the de-rivatives of Ilex paraguariensis (Yerba mate). Very few scientific studies have been conducted on the phytochemical and/or pharmacological properties of its fruits, and practically none on its antimicrobial capacity. The aim of this study was to evaluate the in vitro antifungal capacity of aqueous extracts of I. paraguariensis fruits on dermatophyte fungi.Strains isolated from clinical samples of Trichophyton men-tagrophytes complex, Trichophyton rubrum, Microsporumcanis, Trichophyton tonsurans and Nannizziagypsea were used. To evaluate the antifungal capacity of the aqueous extract of yerba mate (EAFYM), a stock solution of 500 mg/ml was prepared. The quantitative microdilution method was applied in RPMI broth. A fungal inoculum of 1-3 x103 CFU/ml was used. Controls for fungal growth, sterility and commercial reference antifungals were performed. Cultures were incubated for 96 h at 35 °C. The minimum concentration of EAFYM that produced complete inhibition of fungal growth was determined by visual observation and subsequent puncture on solid medium. It is concluded that EAFYM has in vitro antifungal activity against the dermatophyte strains studied, ranging from 31.25 to 125 mg/ml. 2023 artículo científico 0329-8922 https://www.redalyc.org/articulo.oa?id=382679663003 https://www.redalyc.org/journal/3826/382679663003/ https://www.redalyc.org/journal/3826/382679663003/html/ https://www.redalyc.org/journal/3826/382679663003/382679663003.epub https://www.redalyc.org/journal/3826/382679663003/movil 10.36995/j.recyt.2023.39.003 en http://www.redalyc.org/revista.oa?id=3826 Revista de Ciencia y Tecnología application/pdf Universidad Nacional de Misiones Revista de Ciencia y Tecnología (Argentina) Num.1 Vol.39 |
| title | Antifungal capacity of aqueous extracts of ilex paraguariensis fruits against dermatophite fungi |
| topic | Geología Dermatophytes yerba mate fruits antifungal activity |
| url | https://www.redalyc.org/articulo.oa?id=382679663003 https://www.redalyc.org/journal/3826/382679663003/ https://www.redalyc.org/journal/3826/382679663003/html/ https://www.redalyc.org/journal/3826/382679663003/382679663003.epub https://www.redalyc.org/journal/3826/382679663003/movil |