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Autore principale: José Francisco BAUMGRATZ
Natura: Artículo científico
Lingua:en
Pubblicazione: Sociedade Brasileira de Cirurgia Cardiovascular 2010
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Accesso online:https://www.redalyc.org/articulo.oa?id=398941876004
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author José Francisco BAUMGRATZ
author_facet José Francisco BAUMGRATZ
contents Cardiogenic shock due to citomegalovirus myocarditis: successful clinical treatment José Francisco BAUMGRATZ José Henrique Andrade VILA José Pedro da SILVA Luciana da FONSECA Edwal A. Campos RODRIGUES Elias KNOBEL Medicina drug Myocarditis Ganciclovir Pulse therapy Cardiogenic shock Objective: Cytomegalovirus (CMV) systemic disease andmyocarditis in healthy persons is infrequently reported in theliterature, although in increasing numbers in recent years.The importance of the recognition of the syndrome that usuallyhas an initial picture of a mononucleosis like infection in anotherwise healthy person, is the available therapeutic agent,ganciclovir, that can cure the infectious disease.Methods: We analyzed the clinical result of pulsotherapywith steroids in a patient with CMV myocarditis after 7days of etiological treatment, with ganciclovir, intravenousvasodilators, and the conventional treatment for congestiveheart failure.Results: The clinical condition of the patient improvedaccordingly to the better function of the left ventricle, andthe ganciclovir was kept for 21 days, most of it in an outpatient basis. The patient was dismissed from the hospital,with normal myocardial function.Conclusion: Potentially curable forms of myocarditis, likeM pneumoniae and CMV, for example, can have an initialdisproportionate aggression to the myocardium, by the acuteinflammatory reaction, that can by itself make worse thedamage to the LV function. In our opinion, the blockade ofthis process by pulsotherapy with steroids can help in thetreatment of these patients. We understand that the differentscenario of immunosuppressive treatments for the possibleauto immunity of the more chronic forms of the presumablypost viral cardiomyopathy has been in dispute in the literature,and has stolen the focus from the truly acute cases. 2010 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398941876004 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.2 Vol.25
format Artículo científico
id redalyc_398941876004
language en
publishDate 2010
publisher Sociedade Brasileira de Cirurgia Cardiovascular
spellingShingle Cardiogenic shock due to citomegalovirus myocarditis: successful clinical treatment
José Francisco BAUMGRATZ
Medicina
drug
Myocarditis
Ganciclovir
Pulse therapy
Cardiogenic shock
Cardiogenic shock due to citomegalovirus myocarditis: successful clinical treatment José Francisco BAUMGRATZ José Henrique Andrade VILA José Pedro da SILVA Luciana da FONSECA Edwal A. Campos RODRIGUES Elias KNOBEL Medicina drug Myocarditis Ganciclovir Pulse therapy Cardiogenic shock Objective: Cytomegalovirus (CMV) systemic disease andmyocarditis in healthy persons is infrequently reported in theliterature, although in increasing numbers in recent years.The importance of the recognition of the syndrome that usuallyhas an initial picture of a mononucleosis like infection in anotherwise healthy person, is the available therapeutic agent,ganciclovir, that can cure the infectious disease.Methods: We analyzed the clinical result of pulsotherapywith steroids in a patient with CMV myocarditis after 7days of etiological treatment, with ganciclovir, intravenousvasodilators, and the conventional treatment for congestiveheart failure.Results: The clinical condition of the patient improvedaccordingly to the better function of the left ventricle, andthe ganciclovir was kept for 21 days, most of it in an outpatient basis. The patient was dismissed from the hospital,with normal myocardial function.Conclusion: Potentially curable forms of myocarditis, likeM pneumoniae and CMV, for example, can have an initialdisproportionate aggression to the myocardium, by the acuteinflammatory reaction, that can by itself make worse thedamage to the LV function. In our opinion, the blockade ofthis process by pulsotherapy with steroids can help in thetreatment of these patients. We understand that the differentscenario of immunosuppressive treatments for the possibleauto immunity of the more chronic forms of the presumablypost viral cardiomyopathy has been in dispute in the literature,and has stolen the focus from the truly acute cases. 2010 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398941876004 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.2 Vol.25
title Cardiogenic shock due to citomegalovirus myocarditis: successful clinical treatment
topic Medicina
drug
Myocarditis
Ganciclovir
Pulse therapy
Cardiogenic shock
url https://www.redalyc.org/articulo.oa?id=398941876004