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Autor principal: Daniel Lago Borges
Formato: Artículo científico
Lenguaje:en
Publicado: Sociedade Brasileira de Cirurgia Cardiovascular 2013
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Acceso en línea:https://www.redalyc.org/articulo.oa?id=398941890013
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author Daniel Lago Borges
author_facet Daniel Lago Borges
contents Effects of different PEEP levels on respiratory mechanics and oxygenation after coronary artery bypass grafting Daniel Lago Borges Vinícius José da Silva Nina Marina Albuquerque Gonçalves Costa Thiago Eduardo Pereira Baldez Natália Pereira dos Santos Ilka Mendes Lima Eduardo Durans Figuerêdo Josimary Lima da Silva Lula Medicina Oxygenation Positive end expiratory pressure Respiratory mechanics Myocardial revascularization Objective: To compare the effects of different levels of pos - itive end-expiratory pressure on respiratory mechanics and oxygenation indexes in the immediate postoperative period of coronary artery bypass grafting. Methods: Randomized clinical trial in which 136 patients underwent coronary artery bypass grafting between January 2011 and March 2012 were divided into three groups and admitted to mechanical ventilation with different positive end- expiratory pressure levels: Group A, 5 cmH 2 O (n=44), Group B, 8 cmH 2 O (n=47) and Group C, 10 cmH 2 O (n=45). Data about respiratory mechanics were obtained from mechanical ventilator monitor and oxygenation indexes from arterial blood gas samples, collected twenty minutes after intensive care unit admission. Patients with chronic obstructive pulmonary disease and patients submitted to off-pump, emergency or combined operations were not included. For statistical analysis, we used Kruskal-Wallis, G and Chi-square tests, considering results significant when P <0.05. Results: Groups were homogeneous in terms of demographic, clinical and surgical variables. Patients ventilated with positive end-expiratory pressure of 10 cmH 2 O (Group C) had best compliance ( P =0.04) and airway resistance values, this, however, without statistical significance. They also had best oxygenation indexes, with statistical difference in all analyzed variables, and lower frequency of hypoxemia ( P =0.03). Conclusion: Higher levels of positive end-expiratory pressure in immediate postoperative period of coronary artery bypass grafting improved pulmonary compliance values and increased oxygenation indexes, resulting in lower frequency of hypoxemia. 2013 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398941890013 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.3 Vol.28
format Artículo científico
id redalyc_398941890013
language en
publishDate 2013
publisher Sociedade Brasileira de Cirurgia Cardiovascular
spellingShingle Effects of different PEEP levels on respiratory mechanics and oxygenation after coronary artery bypass grafting
Daniel Lago Borges
Medicina
Oxygenation
Positive end
expiratory pressure
Respiratory mechanics
Myocardial revascularization
Effects of different PEEP levels on respiratory mechanics and oxygenation after coronary artery bypass grafting Daniel Lago Borges Vinícius José da Silva Nina Marina Albuquerque Gonçalves Costa Thiago Eduardo Pereira Baldez Natália Pereira dos Santos Ilka Mendes Lima Eduardo Durans Figuerêdo Josimary Lima da Silva Lula Medicina Oxygenation Positive end expiratory pressure Respiratory mechanics Myocardial revascularization Objective: To compare the effects of different levels of pos - itive end-expiratory pressure on respiratory mechanics and oxygenation indexes in the immediate postoperative period of coronary artery bypass grafting. Methods: Randomized clinical trial in which 136 patients underwent coronary artery bypass grafting between January 2011 and March 2012 were divided into three groups and admitted to mechanical ventilation with different positive end- expiratory pressure levels: Group A, 5 cmH 2 O (n=44), Group B, 8 cmH 2 O (n=47) and Group C, 10 cmH 2 O (n=45). Data about respiratory mechanics were obtained from mechanical ventilator monitor and oxygenation indexes from arterial blood gas samples, collected twenty minutes after intensive care unit admission. Patients with chronic obstructive pulmonary disease and patients submitted to off-pump, emergency or combined operations were not included. For statistical analysis, we used Kruskal-Wallis, G and Chi-square tests, considering results significant when P <0.05. Results: Groups were homogeneous in terms of demographic, clinical and surgical variables. Patients ventilated with positive end-expiratory pressure of 10 cmH 2 O (Group C) had best compliance ( P =0.04) and airway resistance values, this, however, without statistical significance. They also had best oxygenation indexes, with statistical difference in all analyzed variables, and lower frequency of hypoxemia ( P =0.03). Conclusion: Higher levels of positive end-expiratory pressure in immediate postoperative period of coronary artery bypass grafting improved pulmonary compliance values and increased oxygenation indexes, resulting in lower frequency of hypoxemia. 2013 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398941890013 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.3 Vol.28
title Effects of different PEEP levels on respiratory mechanics and oxygenation after coronary artery bypass grafting
topic Medicina
Oxygenation
Positive end
expiratory pressure
Respiratory mechanics
Myocardial revascularization
url https://www.redalyc.org/articulo.oa?id=398941890013