Determinants of peak VO2 in heart transplant recipients
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| Natura: | Artículo científico |
| Lingua: | en |
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Sociedade Brasileira de Cirurgia Cardiovascular
2015
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| _version_ | 1876441942232924160 |
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| author | Vitor Oliveira Carvalho |
| author_facet | Vitor Oliveira Carvalho |
| contents | Determinants of peak VO2 in heart transplant recipients Vitor Oliveira Carvalho Guilherme Veiga Guimarães Marcelo Luiz Campos Vieira Aparecida Maria Catai Vagner Oliveira-Carvalho Silvia Moreira Ayub-Ferreira Edimar Alcides Bocchi Medicina Objective:To establish the determinants of the peak VO2 in heart transplant recipients.Methods:Patient's assessment was performed in two consecutive days. In the first day, patients performed the heart rate variability assessment followed by a cardiopulmonary exercise test. In the second day, patients performed a resting echocardiography. Heart transplant recipients were eligible if they were in a stable condition and without any evidence of tissue rejection diagnosed by endomyocardial biopsy. Patients with pacemaker, noncardiovascular functional limitations such as osteoarthritis and chronic obstructive pulmonary disease were excluded from this study.Results:Sixty patients (68% male, 48 years and 64 months following heart transplantation) were assessed. Multivariate analysis selected the following variables: receptor's gender (P=0.001), receptor age (P=0.049), receptor Body Mass Index (P=0.005), heart rate reserve (P <0.0001), left atrium diameter (P=0.016). Multivariate analysis showed r=0.77 and r2=0.6 with P <0.001. Equation: peakVO2=32.851 - 3.708 (receptor gender) - 0.067 (receptor age) - 0.318 (receptor BMI) + 0.145 (heart rate reserve) - 0.111 (left atrium diameter).Conclusion:The determinants of the peak VO2 in heart transplant recipients were: receptor sex, age, Body Mass Index, heart rate reserve and left atrium diameter. Heart rate reserve was the unique variable positively associated with peak VO2. This data suggest the importance of the sympathetic reinnervation in peak VO2 in heart transplant recipients. 2015 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398941896006 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.1 Vol.30 |
| format | Artículo científico |
| id | redalyc_398941896006 |
| institution | Redalyc |
| language | en |
| publishDate | 2015 |
| publisher | Sociedade Brasileira de Cirurgia Cardiovascular |
| spellingShingle | Determinants of peak VO2 in heart transplant recipients Vitor Oliveira Carvalho Medicina Determinants of peak VO2 in heart transplant recipients Vitor Oliveira Carvalho Guilherme Veiga Guimarães Marcelo Luiz Campos Vieira Aparecida Maria Catai Vagner Oliveira-Carvalho Silvia Moreira Ayub-Ferreira Edimar Alcides Bocchi Medicina Objective:To establish the determinants of the peak VO2 in heart transplant recipients.Methods:Patient's assessment was performed in two consecutive days. In the first day, patients performed the heart rate variability assessment followed by a cardiopulmonary exercise test. In the second day, patients performed a resting echocardiography. Heart transplant recipients were eligible if they were in a stable condition and without any evidence of tissue rejection diagnosed by endomyocardial biopsy. Patients with pacemaker, noncardiovascular functional limitations such as osteoarthritis and chronic obstructive pulmonary disease were excluded from this study.Results:Sixty patients (68% male, 48 years and 64 months following heart transplantation) were assessed. Multivariate analysis selected the following variables: receptor's gender (P=0.001), receptor age (P=0.049), receptor Body Mass Index (P=0.005), heart rate reserve (P <0.0001), left atrium diameter (P=0.016). Multivariate analysis showed r=0.77 and r2=0.6 with P <0.001. Equation: peakVO2=32.851 - 3.708 (receptor gender) - 0.067 (receptor age) - 0.318 (receptor BMI) + 0.145 (heart rate reserve) - 0.111 (left atrium diameter).Conclusion:The determinants of the peak VO2 in heart transplant recipients were: receptor sex, age, Body Mass Index, heart rate reserve and left atrium diameter. Heart rate reserve was the unique variable positively associated with peak VO2. This data suggest the importance of the sympathetic reinnervation in peak VO2 in heart transplant recipients. 2015 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398941896006 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.1 Vol.30 |
| title | Determinants of peak VO2 in heart transplant recipients |
| topic | Medicina |
| url | https://www.redalyc.org/articulo.oa?id=398941896006 |