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| Format: | Artículo científico |
| Langue: | en |
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Sociedade Brasileira de Cirurgia Cardiovascular
2015
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| Accès en ligne: | https://www.redalyc.org/articulo.oa?id=398942250012 |
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- Cardiopulmonary bypass increases the risk of vasoplegic syndrome after coronary artery bypass grafting in patients with dialysis-dependent chronic renal failure Nelson Américo Hossne Junior Matheus Miranda Marcus Rodrigo Monteiro João Nelson Rodrigues Branco Guilherme Flora Vargas José Osmar Medina de Abreu Pestana Walter José Gomes Medicina Chronic Renal Insufficiency Vasoplegic Syndrome Cardiopulmonary Bypass Myocardial Revascularization Objective: Coronary artery bypass grafting is currently the best treatment for dialysis patients with multivessel coronary artery involvement. Vasoplegic syndrome of inflammatory eti - ology constitutes an important postoperative complication, with highly negative impact on prognosis. Considering that these patients have an intrinsic inflammatory response exacerbation, our goal was to evaluate the incidence and mortality of vasople - gic syndrome after myocardial revascularization in this group. Methods: A retrospective, single-center study of 50 consec - utive and non-selected dialysis patients who underwent myo - cardial revascularization in a tertiary university hospital, from 2007 to 2012. The patients were divided into 2 groups, according to the use of cardiopulmonary bypass or not (off-pump coro - nary artery bypass). The incidence and mortality of vasoplegic syndrome were analyzed. The subgroup of vasoplegic patients was studied separately. Results: There were no preoperative demographic differences between the cardiopulmonary bypass (n=20) and off-pump cor - onary artery bypass (n=30) group. Intraoperative data showed a greater number of distal coronary arteries anastomosis (2.8 vs. 1.8, P <0.0001) and higher transfusion rates (65% vs. 23%, P =0.008) in the cardiopulmonary bypass group. Vasoplegia in - cidence was statistically higher ( P =0.0124) in the cardiopulmo - nary bypass group (30%) compared to the off-pump coronary artery bypass group (3%). Vasoplegia mortality was 50% in the cardiopulmonary bypass group and 0% in the off-pump cor - onary artery bypass group. The vasoplegic subgroup analysis showed no statistically significant clinical differences. Conclusion: Cardiopulmonary bypass increased the risk for developing postoperative vasoplegic syndrome after coro - nary artery bypass grafting in patients with dialysis-dependent chronic renal failure. 2015 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398942250012 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.4 Vol.30