Predictors of Postoperative Acute Kidney Injury after Coronary Artery Bypass Graft Surgery
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Sociedade Brasileira de Cirurgia Cardiovascular
2018
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| _version_ | 1876422406320422912 |
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| author | Christian Ortega-Loubon |
| author_facet | Christian Ortega-Loubon |
| contents | Predictors of Postoperative Acute Kidney Injury after Coronary Artery Bypass Graft Surgery Christian Ortega-Loubon Manuel Fernández-Molina Lucía Pañeda-Delgado Pablo Jorge-Monjas Yolanda Carrascal Medicina Risk Factors Risk Assessment Acute Kidney Injury Coronary Artery Bypass Calcium Channel Blockers Objective: The aims of this study were to identify the risk factors associated with acute kidney injury (AKI) after isolated surgical revascularization with cardiopulmonary bypass and to develop a model to predict the appearance of postoperative AKI.Methods: A total of 435 adult patients who underwent primary isolated coronary artery bypass graft (CABG) surgery, from 2012 to 2016, in the Clinic University Hospital of Valladolid (Spain) were enrolled. AKI was defined according to the risk, injury, failure, loss, and end-stage (RIFLE) criteria. Data were collected from hospital electronic medical records. Multiple logistic regression analysis was used to identify risk factors.Results: The prevalence of AKI was 12.4%. Multivariate analysis identified age (odds ratio OR, 1.056; 95% confidence interval CI, 1.016-1.098; P=0.005), hypertension (OR, 3.078; 95% CI, 1.151-8.230;P=0.018), low ejection fraction (EF) (OR, 6.785; 95% CI, 2.080-22.135; P=0.001), estimated glomerular filtration rate (eGFR) (OR, 1.017; 95% CI, 1.005-1.028; P=0.014), EuroSCORE II (OR, 1.049; 95% CI, 1.004-1.096; P=0.033), and no intake of calcium-channel blockers (CCB) (OR, 4.892; 95% CI, 1.496-16.025; P=0.022) as risk factors for AKI. These risk factors were included in a model to predict postoperative AKI with an area under a receiver operating characteristic curve of 0.783±0.036 (95% CI, 0.713-0.854; P<0.0001).Conclusion: Age, hypertension, low EF, eGFR, EuroSCORE II, and no intake of CCB were independent risk factors for postoperative AKI. These factors provide an easy and accurate model to predict postoperative AKI in patients undergoing cardiac surgery. 2018 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398956442004 https://www.redalyc.org/journal/3989/398956442004/ https://www.redalyc.org/journal/3989/398956442004/html/ https://www.redalyc.org/journal/3989/398956442004/398956442004.epub https://www.redalyc.org/journal/3989/398956442004/movil 10.21470/1678-9741-2017-0251 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.4 Vol.33 |
| format | Artículo científico |
| id | redalyc_398956442004 |
| institution | Redalyc |
| language | en |
| publishDate | 2018 |
| publisher | Sociedade Brasileira de Cirurgia Cardiovascular |
| spellingShingle | Predictors of Postoperative Acute Kidney Injury after Coronary Artery Bypass Graft Surgery Christian Ortega-Loubon Medicina Risk Factors Risk Assessment Acute Kidney Injury Coronary Artery Bypass Calcium Channel Blockers Predictors of Postoperative Acute Kidney Injury after Coronary Artery Bypass Graft Surgery Christian Ortega-Loubon Manuel Fernández-Molina Lucía Pañeda-Delgado Pablo Jorge-Monjas Yolanda Carrascal Medicina Risk Factors Risk Assessment Acute Kidney Injury Coronary Artery Bypass Calcium Channel Blockers Objective: The aims of this study were to identify the risk factors associated with acute kidney injury (AKI) after isolated surgical revascularization with cardiopulmonary bypass and to develop a model to predict the appearance of postoperative AKI.Methods: A total of 435 adult patients who underwent primary isolated coronary artery bypass graft (CABG) surgery, from 2012 to 2016, in the Clinic University Hospital of Valladolid (Spain) were enrolled. AKI was defined according to the risk, injury, failure, loss, and end-stage (RIFLE) criteria. Data were collected from hospital electronic medical records. Multiple logistic regression analysis was used to identify risk factors.Results: The prevalence of AKI was 12.4%. Multivariate analysis identified age (odds ratio OR, 1.056; 95% confidence interval CI, 1.016-1.098; P=0.005), hypertension (OR, 3.078; 95% CI, 1.151-8.230;P=0.018), low ejection fraction (EF) (OR, 6.785; 95% CI, 2.080-22.135; P=0.001), estimated glomerular filtration rate (eGFR) (OR, 1.017; 95% CI, 1.005-1.028; P=0.014), EuroSCORE II (OR, 1.049; 95% CI, 1.004-1.096; P=0.033), and no intake of calcium-channel blockers (CCB) (OR, 4.892; 95% CI, 1.496-16.025; P=0.022) as risk factors for AKI. These risk factors were included in a model to predict postoperative AKI with an area under a receiver operating characteristic curve of 0.783±0.036 (95% CI, 0.713-0.854; P<0.0001).Conclusion: Age, hypertension, low EF, eGFR, EuroSCORE II, and no intake of CCB were independent risk factors for postoperative AKI. These factors provide an easy and accurate model to predict postoperative AKI in patients undergoing cardiac surgery. 2018 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398956442004 https://www.redalyc.org/journal/3989/398956442004/ https://www.redalyc.org/journal/3989/398956442004/html/ https://www.redalyc.org/journal/3989/398956442004/398956442004.epub https://www.redalyc.org/journal/3989/398956442004/movil 10.21470/1678-9741-2017-0251 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.4 Vol.33 |
| title | Predictors of Postoperative Acute Kidney Injury after Coronary Artery Bypass Graft Surgery |
| topic | Medicina Risk Factors Risk Assessment Acute Kidney Injury Coronary Artery Bypass Calcium Channel Blockers |
| url | https://www.redalyc.org/articulo.oa?id=398956442004 https://www.redalyc.org/journal/3989/398956442004/ https://www.redalyc.org/journal/3989/398956442004/html/ https://www.redalyc.org/journal/3989/398956442004/398956442004.epub https://www.redalyc.org/journal/3989/398956442004/movil |