Consequence of Ischemic Stroke after Coronary Surgery with Cardiopulmonary Bypass According to Stroke Subtypes

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Main Author: Mustafa Aldag
Format: Artículo científico
Language:en
Published: Sociedade Brasileira de Cirurgia Cardiovascular 2018
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author Mustafa Aldag
author_facet Mustafa Aldag
contents Consequence of Ischemic Stroke after Coronary Surgery with Cardiopulmonary Bypass According to Stroke Subtypes Mustafa Aldag Cemal Kocaaslan Mehmet Senel Bademci Zeynep Yildiz Aydin Kahraman Ahmet Oztekin Mehmet Yilmaz Tamer Kehlibar Bulend Ketenci Ebuzer Aydin Medicina Stroke Adverse Effects Coronary Artery Bypass Cardiopulmonary Bypass Introduction: The aim of this study was to determine the outcomes of patients developing ischemic stroke after coronary artery bypass grafting (CABG). Methods: From March 2012 to January 2017, 5380 consecutive patients undergoing elective coronary surgery were analyzed. Ninety-five patients who developed ischemic strokes after on-pump coronary surgery were included in the study, retrospectively. The cohort was divided into four subgroups [total anterior circulation infarction (TACI), partial anterior circulation infarction (PACI), posterior circulation infarction (POCI), and lacunar infarction (LACI)] according to the Oxfordshire Community Stroke Project (OCSP) classification. The primary endpoints were in-hospital mortality, total mortality, and survival analysis over an average of 30 months of followup. The secondary endpoints were the extent of disability and dependency according to modified Rankin Scale (mRS). Results: The incidence of stroke was 1.76% (n=95). The median age was 62.03±10.06 years and 68 (71.6%) patients were male. The groups were as follows: TACI (n=17, 17.9%), PACI (n=47, 49.5%), POCI (n=20, 21.1%), and LACI (n=11, 11.6%). Twenty-eight (29.5%) patients died in hospital and 34 (35.8%) deaths occurred. The overall mortality rate of the TACI group was significantly higher than that of the LACI group (64.7% vs. 27.3%, P=0.041). The mean mRS score of the TACI group was significantly higher than that of the other groups (P=0.003). Conclusion: Patients in the TACI group had higher inhospital and cumulative mortality rates and higher mRS scores. We believe that use of the OCSP classification and the mRS may render it possible to predict the outcomes of stroke after coronary surgery. 2018 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398957528007 https://www.redalyc.org/journal/3989/398957528007/ https://www.redalyc.org/journal/3989/398957528007/html/ https://www.redalyc.org/journal/3989/398957528007/398957528007.epub https://www.redalyc.org/journal/3989/398957528007/movil 10.21470/1678-9741-2018-0086 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.5 Vol.33
format Artículo científico
id redalyc_398957528007
institution Redalyc
language en
publishDate 2018
publisher Sociedade Brasileira de Cirurgia Cardiovascular
spellingShingle Consequence of Ischemic Stroke after Coronary Surgery with Cardiopulmonary Bypass According to Stroke Subtypes
Mustafa Aldag
Medicina
Stroke
Adverse Effects
Coronary Artery Bypass
Cardiopulmonary Bypass
Consequence of Ischemic Stroke after Coronary Surgery with Cardiopulmonary Bypass According to Stroke Subtypes Mustafa Aldag Cemal Kocaaslan Mehmet Senel Bademci Zeynep Yildiz Aydin Kahraman Ahmet Oztekin Mehmet Yilmaz Tamer Kehlibar Bulend Ketenci Ebuzer Aydin Medicina Stroke Adverse Effects Coronary Artery Bypass Cardiopulmonary Bypass Introduction: The aim of this study was to determine the outcomes of patients developing ischemic stroke after coronary artery bypass grafting (CABG). Methods: From March 2012 to January 2017, 5380 consecutive patients undergoing elective coronary surgery were analyzed. Ninety-five patients who developed ischemic strokes after on-pump coronary surgery were included in the study, retrospectively. The cohort was divided into four subgroups [total anterior circulation infarction (TACI), partial anterior circulation infarction (PACI), posterior circulation infarction (POCI), and lacunar infarction (LACI)] according to the Oxfordshire Community Stroke Project (OCSP) classification. The primary endpoints were in-hospital mortality, total mortality, and survival analysis over an average of 30 months of followup. The secondary endpoints were the extent of disability and dependency according to modified Rankin Scale (mRS). Results: The incidence of stroke was 1.76% (n=95). The median age was 62.03±10.06 years and 68 (71.6%) patients were male. The groups were as follows: TACI (n=17, 17.9%), PACI (n=47, 49.5%), POCI (n=20, 21.1%), and LACI (n=11, 11.6%). Twenty-eight (29.5%) patients died in hospital and 34 (35.8%) deaths occurred. The overall mortality rate of the TACI group was significantly higher than that of the LACI group (64.7% vs. 27.3%, P=0.041). The mean mRS score of the TACI group was significantly higher than that of the other groups (P=0.003). Conclusion: Patients in the TACI group had higher inhospital and cumulative mortality rates and higher mRS scores. We believe that use of the OCSP classification and the mRS may render it possible to predict the outcomes of stroke after coronary surgery. 2018 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398957528007 https://www.redalyc.org/journal/3989/398957528007/ https://www.redalyc.org/journal/3989/398957528007/html/ https://www.redalyc.org/journal/3989/398957528007/398957528007.epub https://www.redalyc.org/journal/3989/398957528007/movil 10.21470/1678-9741-2018-0086 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.5 Vol.33
title Consequence of Ischemic Stroke after Coronary Surgery with Cardiopulmonary Bypass According to Stroke Subtypes
topic Medicina
Stroke
Adverse Effects
Coronary Artery Bypass
Cardiopulmonary Bypass
url https://www.redalyc.org/articulo.oa?id=398957528007
https://www.redalyc.org/journal/3989/398957528007/
https://www.redalyc.org/journal/3989/398957528007/html/
https://www.redalyc.org/journal/3989/398957528007/398957528007.epub
https://www.redalyc.org/journal/3989/398957528007/movil