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| Natura: | Artículo científico |
| Lingua: | en |
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Sociedade Brasileira de Cirurgia Cardiovascular
2019
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| Accesso online: | https://www.redalyc.org/articulo.oa?id=398959097009 https://www.redalyc.org/journal/3989/398959097009/ https://www.redalyc.org/journal/3989/398959097009/html/ https://www.redalyc.org/journal/3989/398959097009/398959097009.epub https://www.redalyc.org/journal/3989/398959097009/movil |
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Sommario:
- Diagnostic Performance of QFR for the Evaluation of Intermediate Coronary Artery Stenosis Confirmed by Fractional Flow Reserve Zhenhua Xing Junyu Pei Jiabing Huang Xinqun Hu Shan Gao Medicina Meta Coronary Artery Disease Quantitative Flow Ratio Analysis Publication Type Sensitivity and Specificity Introduction: Quantitative flow ratio (QFR) is a novel method enabling efficient computation of FFR from three-dimensional quantitative coronary angiography (3D QCA) and thrombolysis in myocardial infarction (TIMI) frame counting. We decided to perform a systematic review and quantitative meta-analysis of the literature to determine the correlation between the diagnosis of functionally significant stenosis obtained by QFR versus FFR and to determine the diagnostic accuracy of QFR for intermediate coronary artery stenosis. Methods: We searched PubMed, Embase, and Web of Science for studies concerning the diagnostic performance of QFR. Our meta-analysis was performed using the DerSimonian and Laird random effects model to determine sensitivity, specificity, positive likelihood ratio (LR+), negative likelihood ratio (LR-), and diagnostic odds ratio (DOR). The sROC was used to determine diagnostic test accuracy. Results: Nine studies consisting of 1175 vessels in 1047 patients were included in our study. The pooled sensitivity, specificity, LR+, LR-, and DOR for QFR were 0.89 (95% CI: 0.86-0.92), 0.88 (95% CI: 0.86-0.91), 6.86 (95% CI,: 5.22-9.02), 0.14 (95% CI: 0.10-0.21), and 53.05 (95% CI: 29.75-94.58), respectively. The area under the summary receiver operating characteristic (sROC) curve for QFR was 0.94. Conclusion: QFR is a simple, useful, and noninvasive modality for diagnosis of functional significance of intermediate coronary artery stenosis. 2019 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398959097009 https://www.redalyc.org/journal/3989/398959097009/ https://www.redalyc.org/journal/3989/398959097009/html/ https://www.redalyc.org/journal/3989/398959097009/398959097009.epub https://www.redalyc.org/journal/3989/398959097009/movil 10.21470/1678-9741-2018-0234 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.2 Vol.34