Surgical Treatment for Congenital Heart Defects in Down Syndrome Patients
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| Lingua: | en |
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Sociedade Brasileira de Cirurgia Cardiovascular
2019
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| _version_ | 1876465557667053568 |
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| author | Fernando Cesar Gimenes Barbosa Santos |
| author_facet | Fernando Cesar Gimenes Barbosa Santos |
| contents | Surgical Treatment for Congenital Heart Defects in Down Syndrome Patients Fernando Cesar Gimenes Barbosa Santos Ulisses Alexandre Croti Carlos Henrique De Marchi Alexandre Noboru Murakami Juliana Dane Pereira Brachine Bruna Cury Borim Renata Geron Finoti Moacir Fernandes de Godoy Medicina Database Congenital Down Syndrome Heart Defects Objective: To analyze data related to surgical treatment in patients with congenital heart defects (CHD) and Down syndrome (DS) based on information from International Quality Improvement Collaborative Database for Congenital Heart Disease (IQIC). Methods: Between July 1, 2010 and December 31, 2017, 139 patients with CHD and DS underwent surgery at Hospital de Base and Hospital da Criança e Maternidade de São José do Rio Preto (FUNFARME)/Faculdade de Medicina de São José do Rio Preto – SP (FAMERP). A quantitative, observational and cross-sectional study was performed in which the pre, intra and postoperative data were analyzed in an IQIC database. The data included gender, age, prematurity, weight, preoperative procedures, diagnosis, associated cardiac and non-cardiac anomalies, Risk Adjustment for Congenital Heart Surgery (RACHS-1), type of surgery, cardiopulmonary bypass (CPB), perfusion time, aortic clamping time and CPB temperature, bacterial sepsis, surgical site infection and other infections, length of stay in intensive care unit (ICU), length of hospital stay and in-hospital mortality. Results: The most prevalent procedures were complete atrioventricular septal defect repair (58 – 39.45%), followed by closure of ventricular septal defect (36 – 24.49%). The RACHS-1 categories 1, 2, 3 and 4 were distributed as 22 (15%); 49 (33.3%); 72 (49%) and 4 (2.7%), respectively. There were no procedures classified as categories 5 or 6. Bacterial sepsis occurred in 10.2% of cases, surgical site infection in 6.1%, other infections in 14.3%. The median length of ICU stay was 5 days and the median length of hospital stay was 11 days. In-hospital mortality was 6.8%. Conclusion: Surgical treatment in patients with CHD and DS usually does not require highly complex surgical procedures, but are affected by infectious complications, resulting in a longer ICU and hospital length of stay with considerable mortality 2019 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398964872002 https://www.redalyc.org/journal/3989/398964872002/ https://www.redalyc.org/journal/3989/398964872002/html/ https://www.redalyc.org/journal/3989/398964872002/398964872002.epub https://www.redalyc.org/journal/3989/398964872002/movil 10.21470/1678-9741-2018-0358 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.1 Vol.34 |
| format | Artículo científico |
| id | redalyc_398964872002 |
| institution | Redalyc |
| language | en |
| publishDate | 2019 |
| publisher | Sociedade Brasileira de Cirurgia Cardiovascular |
| spellingShingle | Surgical Treatment for Congenital Heart Defects in Down Syndrome Patients Fernando Cesar Gimenes Barbosa Santos Medicina Database Congenital Down Syndrome Heart Defects Surgical Treatment for Congenital Heart Defects in Down Syndrome Patients Fernando Cesar Gimenes Barbosa Santos Ulisses Alexandre Croti Carlos Henrique De Marchi Alexandre Noboru Murakami Juliana Dane Pereira Brachine Bruna Cury Borim Renata Geron Finoti Moacir Fernandes de Godoy Medicina Database Congenital Down Syndrome Heart Defects Objective: To analyze data related to surgical treatment in patients with congenital heart defects (CHD) and Down syndrome (DS) based on information from International Quality Improvement Collaborative Database for Congenital Heart Disease (IQIC). Methods: Between July 1, 2010 and December 31, 2017, 139 patients with CHD and DS underwent surgery at Hospital de Base and Hospital da Criança e Maternidade de São José do Rio Preto (FUNFARME)/Faculdade de Medicina de São José do Rio Preto – SP (FAMERP). A quantitative, observational and cross-sectional study was performed in which the pre, intra and postoperative data were analyzed in an IQIC database. The data included gender, age, prematurity, weight, preoperative procedures, diagnosis, associated cardiac and non-cardiac anomalies, Risk Adjustment for Congenital Heart Surgery (RACHS-1), type of surgery, cardiopulmonary bypass (CPB), perfusion time, aortic clamping time and CPB temperature, bacterial sepsis, surgical site infection and other infections, length of stay in intensive care unit (ICU), length of hospital stay and in-hospital mortality. Results: The most prevalent procedures were complete atrioventricular septal defect repair (58 – 39.45%), followed by closure of ventricular septal defect (36 – 24.49%). The RACHS-1 categories 1, 2, 3 and 4 were distributed as 22 (15%); 49 (33.3%); 72 (49%) and 4 (2.7%), respectively. There were no procedures classified as categories 5 or 6. Bacterial sepsis occurred in 10.2% of cases, surgical site infection in 6.1%, other infections in 14.3%. The median length of ICU stay was 5 days and the median length of hospital stay was 11 days. In-hospital mortality was 6.8%. Conclusion: Surgical treatment in patients with CHD and DS usually does not require highly complex surgical procedures, but are affected by infectious complications, resulting in a longer ICU and hospital length of stay with considerable mortality 2019 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398964872002 https://www.redalyc.org/journal/3989/398964872002/ https://www.redalyc.org/journal/3989/398964872002/html/ https://www.redalyc.org/journal/3989/398964872002/398964872002.epub https://www.redalyc.org/journal/3989/398964872002/movil 10.21470/1678-9741-2018-0358 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.1 Vol.34 |
| title | Surgical Treatment for Congenital Heart Defects in Down Syndrome Patients |
| topic | Medicina Database Congenital Down Syndrome Heart Defects |
| url | https://www.redalyc.org/articulo.oa?id=398964872002 https://www.redalyc.org/journal/3989/398964872002/ https://www.redalyc.org/journal/3989/398964872002/html/ https://www.redalyc.org/journal/3989/398964872002/398964872002.epub https://www.redalyc.org/journal/3989/398964872002/movil |