Usefulness of Immature Granulocytes as A Prognostic Factor in ST-Elevation Myocardial Infarction
Fuente:
Redalyc
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Artículo científico |
| Sprache: | en |
| Veröffentlicht: |
Sociedade Brasileira de Cirurgia Cardiovascular
2022
|
| Schlagworte: | |
| Online-Zugang: | |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| _version_ | 1876470224468836352 |
|---|---|
| author | Mustafa Korkut |
| author_facet | Mustafa Korkut |
| contents | Usefulness of Immature Granulocytes as A Prognostic Factor in ST-Elevation Myocardial Infarction Mustafa Korkut Cihan Bedel Ramazan Sivil Mücahit Alp Arslan Fatih Selvi Görkem Kuş Ökkeş Zortuk Medicina ST Granulocytes Inflammation Disease Management Segment Elevation Myocardial Infarction Objective: ST-segment elevation myocardial infarction (STEMI) is a serious, life-threatening disease. Inflammatory markers have recently become the focus of attention in the assessment of severity in the early stages of STEMI. This study aimed to evaluate the importance of immature granulocytes (IG) as a prognostic marker in STEMI. Methods: Patients admitted to the coronary care unit with a diagnosis of STEMI and who underwent primary percutaneous coronary intervention (pPCI) within the period from January 1, 2019 to January 1, 2020, were retrospectively scanned. A total of 146 patients were analised; of these, 112 (76.7%) were male and 34 (33.3) were female, with a mean age of 62.65±14.06 years. Patients’ age, gender, haemogram, biochemistry, and mortality results were recorded. The patientswere divided into two groups as low (<0.6) and high (≥0.6) IG levels and compared. Results: The mean IG levels were significantly higher in the non-survivor group compared to the survivor group (1.12±0.22 vs. 0.50±0.28, P<0.001). Mortality rates were significantly higher in the high IG group compared to the low IG group (26.9% vs. 9.6%, P=0.006). IG was shown to predict mortality with a sensitivity of 72.2% and a specificity of 77.8% at a cut-off value of 0.65 (area under the curve: 0.740, 95% CI: 0.635-0.846, P<0.001). Conclusion: High IG values in the blood collected at the time of admission to the emergency department are a marker of mortality in patients with STEMI. 2022 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398973636015 https://www.redalyc.org/journal/3989/398973636015/ https://www.redalyc.org/journal/3989/398973636015/html/ https://www.redalyc.org/journal/3989/398973636015/398973636015.epub https://www.redalyc.org/journal/3989/398973636015/movil 10.21470/1678-9741-2021-0088 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.6 Vol.37 |
| format | Artículo científico |
| id | redalyc_398973636015 |
| institution | Redalyc |
| language | en |
| publishDate | 2022 |
| publisher | Sociedade Brasileira de Cirurgia Cardiovascular |
| spellingShingle | Usefulness of Immature Granulocytes as A Prognostic Factor in ST-Elevation Myocardial Infarction Mustafa Korkut Medicina ST Granulocytes Inflammation Disease Management Segment Elevation Myocardial Infarction Usefulness of Immature Granulocytes as A Prognostic Factor in ST-Elevation Myocardial Infarction Mustafa Korkut Cihan Bedel Ramazan Sivil Mücahit Alp Arslan Fatih Selvi Görkem Kuş Ökkeş Zortuk Medicina ST Granulocytes Inflammation Disease Management Segment Elevation Myocardial Infarction Objective: ST-segment elevation myocardial infarction (STEMI) is a serious, life-threatening disease. Inflammatory markers have recently become the focus of attention in the assessment of severity in the early stages of STEMI. This study aimed to evaluate the importance of immature granulocytes (IG) as a prognostic marker in STEMI. Methods: Patients admitted to the coronary care unit with a diagnosis of STEMI and who underwent primary percutaneous coronary intervention (pPCI) within the period from January 1, 2019 to January 1, 2020, were retrospectively scanned. A total of 146 patients were analised; of these, 112 (76.7%) were male and 34 (33.3) were female, with a mean age of 62.65±14.06 years. Patients’ age, gender, haemogram, biochemistry, and mortality results were recorded. The patientswere divided into two groups as low (<0.6) and high (≥0.6) IG levels and compared. Results: The mean IG levels were significantly higher in the non-survivor group compared to the survivor group (1.12±0.22 vs. 0.50±0.28, P<0.001). Mortality rates were significantly higher in the high IG group compared to the low IG group (26.9% vs. 9.6%, P=0.006). IG was shown to predict mortality with a sensitivity of 72.2% and a specificity of 77.8% at a cut-off value of 0.65 (area under the curve: 0.740, 95% CI: 0.635-0.846, P<0.001). Conclusion: High IG values in the blood collected at the time of admission to the emergency department are a marker of mortality in patients with STEMI. 2022 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398973636015 https://www.redalyc.org/journal/3989/398973636015/ https://www.redalyc.org/journal/3989/398973636015/html/ https://www.redalyc.org/journal/3989/398973636015/398973636015.epub https://www.redalyc.org/journal/3989/398973636015/movil 10.21470/1678-9741-2021-0088 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.6 Vol.37 |
| title | Usefulness of Immature Granulocytes as A Prognostic Factor in ST-Elevation Myocardial Infarction |
| topic | Medicina ST Granulocytes Inflammation Disease Management Segment Elevation Myocardial Infarction |
| url | https://www.redalyc.org/articulo.oa?id=398973636015 https://www.redalyc.org/journal/3989/398973636015/ https://www.redalyc.org/journal/3989/398973636015/html/ https://www.redalyc.org/journal/3989/398973636015/398973636015.epub https://www.redalyc.org/journal/3989/398973636015/movil |