Sex-Based Differences in One-Year Outcomes After Mitral Valve Repair for Infective Endocarditis
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| Natura: | Artículo científico |
| Lingua: | en |
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Sociedade Brasileira de Cirurgia Cardiovascular
2023
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| author | Zeinab Mohseni Afshar |
| author_facet | Zeinab Mohseni Afshar |
| contents | Sex-Based Differences in One-Year Outcomes After Mitral Valve Repair for Infective Endocarditis Zeinab Mohseni Afshar Feridoun Sabzi Maria Shirvani Nahid Salehi Nasim Nemati Werya Kheradmand Hadis Torbati Mohammad Rouzbahani Medicina Sex checklist reoperation endocarditis treatment outcome Introduction: This study was aimed to evaluate the sex-based differences in baseline characteristics and one-year outcomes of men and women undergoing mitral valve repair for infective endocarditis.Methods: This cross-sectional study was performed at Imam Ali Hospital affiliated with the Kermanshah University of Medical Science. From March 21, 2014, to October 21, 2021, all patients who underwent mitral valve repair for infective endocarditis were enrolled in this study. Data were obtained using a checklist developed based on the study’s objectives. Independent samples t-tests, paired samples t-tests, and chi-squared test (or Fisher’s exact test) were used to assess the differences between subgroups.Results: Of 75 patients, 26 were women (34.7%) and 49 were men (65.3%). Women were more likely to have diabetes mellitus (20.4% vs. 57.7%,P=0.0001), hypertension (49% vs.80.8%, P=0.007), and hypercholesterolemia (55.1% vs. 80.8%, P=0.027). Conversely, men were more likely to have a history of smoking (38.8% vs. 7.7%, P=0.004). After one year, women had significantly higher mortality (0% vs. 7.7%, P=0.049), major adverse cardiac and cerebrovascular events (51.0 vs. 76.9, P=0.029), mitral valve reoperation (8.1% vs. 34.6%, P=0.003), and treatment failure (30.6% vs. 61.5%, P=0.009) rates than men.Conclusion: Mortality, major adverse cardiac and cerebrovascular events, mitral valve reoperation, and treatment failure rates were higher in women than in men. The worse outcomes in women may be explained by their more adverse clinical risk profile. 2023 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398975506007 https://www.redalyc.org/journal/3989/398975506007/ https://www.redalyc.org/journal/3989/398975506007/html/ https://www.redalyc.org/journal/3989/398975506007/398975506007.epub https://www.redalyc.org/journal/3989/398975506007/movil https://doi.org/10.21470/1678-9741-2021-0333 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.5 Vol.38 |
| format | Artículo científico |
| id | redalyc_398975506007 |
| institution | Redalyc |
| language | en |
| publishDate | 2023 |
| publisher | Sociedade Brasileira de Cirurgia Cardiovascular |
| spellingShingle | Sex-Based Differences in One-Year Outcomes After Mitral Valve Repair for Infective Endocarditis Zeinab Mohseni Afshar Medicina Sex checklist reoperation endocarditis treatment outcome Sex-Based Differences in One-Year Outcomes After Mitral Valve Repair for Infective Endocarditis Zeinab Mohseni Afshar Feridoun Sabzi Maria Shirvani Nahid Salehi Nasim Nemati Werya Kheradmand Hadis Torbati Mohammad Rouzbahani Medicina Sex checklist reoperation endocarditis treatment outcome Introduction: This study was aimed to evaluate the sex-based differences in baseline characteristics and one-year outcomes of men and women undergoing mitral valve repair for infective endocarditis.Methods: This cross-sectional study was performed at Imam Ali Hospital affiliated with the Kermanshah University of Medical Science. From March 21, 2014, to October 21, 2021, all patients who underwent mitral valve repair for infective endocarditis were enrolled in this study. Data were obtained using a checklist developed based on the study’s objectives. Independent samples t-tests, paired samples t-tests, and chi-squared test (or Fisher’s exact test) were used to assess the differences between subgroups.Results: Of 75 patients, 26 were women (34.7%) and 49 were men (65.3%). Women were more likely to have diabetes mellitus (20.4% vs. 57.7%,P=0.0001), hypertension (49% vs.80.8%, P=0.007), and hypercholesterolemia (55.1% vs. 80.8%, P=0.027). Conversely, men were more likely to have a history of smoking (38.8% vs. 7.7%, P=0.004). After one year, women had significantly higher mortality (0% vs. 7.7%, P=0.049), major adverse cardiac and cerebrovascular events (51.0 vs. 76.9, P=0.029), mitral valve reoperation (8.1% vs. 34.6%, P=0.003), and treatment failure (30.6% vs. 61.5%, P=0.009) rates than men.Conclusion: Mortality, major adverse cardiac and cerebrovascular events, mitral valve reoperation, and treatment failure rates were higher in women than in men. The worse outcomes in women may be explained by their more adverse clinical risk profile. 2023 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398975506007 https://www.redalyc.org/journal/3989/398975506007/ https://www.redalyc.org/journal/3989/398975506007/html/ https://www.redalyc.org/journal/3989/398975506007/398975506007.epub https://www.redalyc.org/journal/3989/398975506007/movil https://doi.org/10.21470/1678-9741-2021-0333 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.5 Vol.38 |
| title | Sex-Based Differences in One-Year Outcomes After Mitral Valve Repair for Infective Endocarditis |
| topic | Medicina Sex checklist reoperation endocarditis treatment outcome |
| url | https://www.redalyc.org/articulo.oa?id=398975506007 https://www.redalyc.org/journal/3989/398975506007/ https://www.redalyc.org/journal/3989/398975506007/html/ https://www.redalyc.org/journal/3989/398975506007/398975506007.epub https://www.redalyc.org/journal/3989/398975506007/movil https://doi.org/10.21470/1678-9741-2021-0333 |