New-Onset Atrial Fibrillation Following Isolated Coronary Artery Bypass Grafting: Is Pulmonary Hypertension a Risk Factor?
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| Natura: | Artículo científico |
| Lingua: | en |
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Sociedade Brasileira de Cirurgia Cardiovascular
2025
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| _version_ | 1876457826838118400 |
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| author | Barış Akça |
| author_facet | Barış Akça |
| contents | New-Onset Atrial Fibrillation Following Isolated Coronary Artery Bypass Grafting: Is Pulmonary Hypertension a Risk Factor? Barış Akça Nevzat Erdil Medicina Pulmonary Risk Factors Hypertension Atrial Fibrillation Coronary Artery Bypass This study aimed to clarify whether pulmonary hypertension is a risk factor for postoperative new-onset atrial fibrillation (NOAF) following isolated coronary artery bypass grafting (CABG). Methods: Data of 4,782 patients were retrospectively examined from clinical database, and data of isolated CABG performed patients (n = 854) with preoperative echocardiography including pulmonary artery pressure (PAP) measurement were enrolled in study. While 115 patients had post-CABG NOAF (atrial fibrillation [AF] group), 739 did not have AF (non-AF group). Demographic, clinical, and treatment-related parameters were compared between groups, and independent clinical predictors of NOAF were identified by multivariate analysis. Results: Patients of AF group were significantly older and had higher European System for Cardiac Operative Risk Evaluation (EuroSCORE) points, significantly elevated mean systolic PAP, and more pulmonary hypertension. Multivariate regression analysis revealed that mean systolic PAP (odds ratio [OR]: 1.027, 95% confidence interval [CI]: 1.006 - 1.048) and pulmonary hypertension (≥ 30 mmHg; OR: 1.659, 95% CI: 1.093 - 2.518) were independent risk factors for post-CABG NOAF. Chronic obstructive pulmonary disease (COPD) (OR: 2.033, 95% CI: 1.265 - 3.268) and mean duration of ventilation support (OR: 1.059, 95% CI: 1.017 - 1.104) were additionally determined as risk factors for post-CABG NOAF. Conclusion: This study identified patients’ age, high EuroSCORE points, presence of COPD, prolonged ventilation support, and increased PAP as predictors of post-CABG NOAF. Understanding the risk factors will provide better guidance in preventing this complication and its potential consequences. Prospective randomized controlled trials are required to further validate these findings and provide more robust evidence. 2025 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398982402012 https://www.redalyc.org/journal/3989/398982402012/ https://www.redalyc.org/journal/3989/398982402012/html/ https://www.redalyc.org/journal/3989/398982402012/398982402012.epub https://www.redalyc.org/journal/3989/398982402012/movil 10.21470/1678-9741-2024-0352 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.5 Vol.40 |
| format | Artículo científico |
| id | redalyc_398982402012 |
| institution | Redalyc |
| language | en |
| publishDate | 2025 |
| publisher | Sociedade Brasileira de Cirurgia Cardiovascular |
| spellingShingle | New-Onset Atrial Fibrillation Following Isolated Coronary Artery Bypass Grafting: Is Pulmonary Hypertension a Risk Factor? Barış Akça Medicina Pulmonary Risk Factors Hypertension Atrial Fibrillation Coronary Artery Bypass New-Onset Atrial Fibrillation Following Isolated Coronary Artery Bypass Grafting: Is Pulmonary Hypertension a Risk Factor? Barış Akça Nevzat Erdil Medicina Pulmonary Risk Factors Hypertension Atrial Fibrillation Coronary Artery Bypass This study aimed to clarify whether pulmonary hypertension is a risk factor for postoperative new-onset atrial fibrillation (NOAF) following isolated coronary artery bypass grafting (CABG). Methods: Data of 4,782 patients were retrospectively examined from clinical database, and data of isolated CABG performed patients (n = 854) with preoperative echocardiography including pulmonary artery pressure (PAP) measurement were enrolled in study. While 115 patients had post-CABG NOAF (atrial fibrillation [AF] group), 739 did not have AF (non-AF group). Demographic, clinical, and treatment-related parameters were compared between groups, and independent clinical predictors of NOAF were identified by multivariate analysis. Results: Patients of AF group were significantly older and had higher European System for Cardiac Operative Risk Evaluation (EuroSCORE) points, significantly elevated mean systolic PAP, and more pulmonary hypertension. Multivariate regression analysis revealed that mean systolic PAP (odds ratio [OR]: 1.027, 95% confidence interval [CI]: 1.006 - 1.048) and pulmonary hypertension (≥ 30 mmHg; OR: 1.659, 95% CI: 1.093 - 2.518) were independent risk factors for post-CABG NOAF. Chronic obstructive pulmonary disease (COPD) (OR: 2.033, 95% CI: 1.265 - 3.268) and mean duration of ventilation support (OR: 1.059, 95% CI: 1.017 - 1.104) were additionally determined as risk factors for post-CABG NOAF. Conclusion: This study identified patients’ age, high EuroSCORE points, presence of COPD, prolonged ventilation support, and increased PAP as predictors of post-CABG NOAF. Understanding the risk factors will provide better guidance in preventing this complication and its potential consequences. Prospective randomized controlled trials are required to further validate these findings and provide more robust evidence. 2025 artículo científico 0102-7638 https://www.redalyc.org/articulo.oa?id=398982402012 https://www.redalyc.org/journal/3989/398982402012/ https://www.redalyc.org/journal/3989/398982402012/html/ https://www.redalyc.org/journal/3989/398982402012/398982402012.epub https://www.redalyc.org/journal/3989/398982402012/movil 10.21470/1678-9741-2024-0352 en http://www.redalyc.org/revista.oa?id=3989 Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery application/pdf Sociedade Brasileira de Cirurgia Cardiovascular Revista Brasileira de Cirurgia Cardiovascular/Brazilian Journal of Cardiovascular Surgery (Brasil) Num.5 Vol.40 |
| title | New-Onset Atrial Fibrillation Following Isolated Coronary Artery Bypass Grafting: Is Pulmonary Hypertension a Risk Factor? |
| topic | Medicina Pulmonary Risk Factors Hypertension Atrial Fibrillation Coronary Artery Bypass |
| url | https://www.redalyc.org/articulo.oa?id=398982402012 https://www.redalyc.org/journal/3989/398982402012/ https://www.redalyc.org/journal/3989/398982402012/html/ https://www.redalyc.org/journal/3989/398982402012/398982402012.epub https://www.redalyc.org/journal/3989/398982402012/movil |