Avascular necrosis of the femoral head in sickle cell disease in pediatric patients suffering from hip dysfunction
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| Natura: | Artículo científico |
| Lingua: | en |
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Universidad Nacional de Colombia
2016
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| _version_ | 1876443019033444352 |
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| author | Marcos Almeida-Matos |
| author_facet | Marcos Almeida-Matos |
| contents | Avascular necrosis of the femoral head in sickle cell disease in pediatric patients suffering from hip dysfunction Marcos Almeida-Matos Jandrice Carrasco Luanne Lisle Marilda Castelar Salud Hip NLM ) sickle cell osteonecrosis ( source : MeHS Objective The aim of this study is to verify the prevalence of avascular necrosis (AVN) in pediatric patients with sickle cell anemia and hip dysfunction, and to eval - uate the presence of associated risk factors. Method A cross-sectional study was conducted in a group of 92 patients with sick - le cell disease and hip dysfunction. Clinical and sociodemographic characteristics were collected, and laboratory variables were evaluated. All the subjects under - went radiographic and clinical evaluation of the hip. The participants were divided into two groups: the “AVN Group” consisting of patients with AVN, and the “Com - parison Group” without AVN. Both groups were evaluated in search of factors as - sociated with osteonecrosis of the femoral head. Results 43 (46.7 %) out of 92 individuals presented hip dysfunction, and 13 were diagnosed with AVN (30.2 %). Comparison between groups showed significant differences in time of diagnosis, previous trauma, presence of pain, and mean values of functional scores. Higher percentage rates of fetal hemoglobin, higher platelet counts and lower rates of total hemoglobin were perceived in the Com - parison Group. Conclusions Pediatric patients with sickle cell anemia with hip dysfunction present a prevalence of 39.4 % of osteonecrosis of the femoral head. This was associated with a longer time of diagnosis (97 months), previous trauma in 92 % of patients, and a mean Charnley score of 15 points. Also, an association with lower rate of fe - tal hemoglobin (7.2 versus 11.8) was found, which supports the hypothesis that fe - tal hemoglobin may function as a protective factor against avascular necrosis. 2016 artículo científico 0124-0064 https://www.redalyc.org/articulo.oa?id=42249786014 en http://www.redalyc.org/revista.oa?id=422 Revista de Salud Pública application/pdf Universidad Nacional de Colombia Revista de Salud Pública (Colombia) Num.6 Vol.18 |
| format | Artículo científico |
| id | redalyc_42249786014 |
| institution | Redalyc |
| language | en |
| publishDate | 2016 |
| publisher | Universidad Nacional de Colombia |
| spellingShingle | Avascular necrosis of the femoral head in sickle cell disease in pediatric patients suffering from hip dysfunction Marcos Almeida-Matos Salud Hip NLM ) sickle cell osteonecrosis ( source : MeHS Avascular necrosis of the femoral head in sickle cell disease in pediatric patients suffering from hip dysfunction Marcos Almeida-Matos Jandrice Carrasco Luanne Lisle Marilda Castelar Salud Hip NLM ) sickle cell osteonecrosis ( source : MeHS Objective The aim of this study is to verify the prevalence of avascular necrosis (AVN) in pediatric patients with sickle cell anemia and hip dysfunction, and to eval - uate the presence of associated risk factors. Method A cross-sectional study was conducted in a group of 92 patients with sick - le cell disease and hip dysfunction. Clinical and sociodemographic characteristics were collected, and laboratory variables were evaluated. All the subjects under - went radiographic and clinical evaluation of the hip. The participants were divided into two groups: the “AVN Group” consisting of patients with AVN, and the “Com - parison Group” without AVN. Both groups were evaluated in search of factors as - sociated with osteonecrosis of the femoral head. Results 43 (46.7 %) out of 92 individuals presented hip dysfunction, and 13 were diagnosed with AVN (30.2 %). Comparison between groups showed significant differences in time of diagnosis, previous trauma, presence of pain, and mean values of functional scores. Higher percentage rates of fetal hemoglobin, higher platelet counts and lower rates of total hemoglobin were perceived in the Com - parison Group. Conclusions Pediatric patients with sickle cell anemia with hip dysfunction present a prevalence of 39.4 % of osteonecrosis of the femoral head. This was associated with a longer time of diagnosis (97 months), previous trauma in 92 % of patients, and a mean Charnley score of 15 points. Also, an association with lower rate of fe - tal hemoglobin (7.2 versus 11.8) was found, which supports the hypothesis that fe - tal hemoglobin may function as a protective factor against avascular necrosis. 2016 artículo científico 0124-0064 https://www.redalyc.org/articulo.oa?id=42249786014 en http://www.redalyc.org/revista.oa?id=422 Revista de Salud Pública application/pdf Universidad Nacional de Colombia Revista de Salud Pública (Colombia) Num.6 Vol.18 |
| title | Avascular necrosis of the femoral head in sickle cell disease in pediatric patients suffering from hip dysfunction |
| topic | Salud Hip NLM ) sickle cell osteonecrosis ( source : MeHS |
| url | https://www.redalyc.org/articulo.oa?id=42249786014 |