Eficacia comparativa de un fasciolicida experimental, triclabendazol y closantel en bovinos infectados en forma natural con Fasciola hepatica
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| Format: | Artículo científico |
| Langue: | en |
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Universidad Nacional Autónoma de México
2002
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| _version_ | 1876446647552049152 |
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| author | Pedro Ochoa Galván |
| author_facet | Pedro Ochoa Galván |
| contents | Eficacia comparativa de un fasciolicida experimental, triclabendazol y closantel en bovinos infectados en forma natural con Fasciola hepatica Pedro Ochoa Galván Natividad Montenegro Cristino Yolanda Vera Montenegro Rafael Castillo Bocanegra Alicia Hernández Campos Froylán Ibarra Velarde Multidisciplinaria (Ciencias Naturales y Exactas) CATTLE CHEMOTHERAPY FASCIOLICIDES FASCIOLAHEPATICA The aim of the present study was to determine the efficacy of 5-chloro-2-methylthio-6-(1-naphthyloxy)-ihbenzimidazolecalled compound alfa, which was compared with two commercial fascioliscides through thepercentage of F. hepatica egg-reduction in naturally infected cattle. Forty Holstein-Friesian adult cows, previouslydetermined as positive to fluke eggs by the sedimentation test, were used. They were divided in 4 groups (G) of10 animals each, and were treated with the corresponding dose on day cero. G1 was treated with compound alfaat 12 mg/kg/per os; G2 with triclabendazole at 12 mg/kg/per os; G3 with closantel at 3.5 mg/kg subcutaneously, andG4 remained as the non-treated control. All animals were sampled for feces to carry out coprological examinationson days 15, 8, 0, 7, 14, 21, 28, 60 and 90. Efficacy was assessed on the reduction of egg output on days 14 and 21after the treatment with respect to the control group. Results showed an efficacy of 90.1% and 85.3% for compoundalfa, 91.5% and 96.5% for triclabendazole and 82.1% and 92.1% for closantel. Additional parameters such aspercentage of prevalence, mean number of F. hepatica eggs, standard deviation, extension and intensity effect werealso measured. No statistical differences were found between treatments. It is concluded that all compounds testedconsiderably reduced the percentage of egg excretion, showing an acceptable fasciolicide efficacy. 2002 artículo científico 0301-5092 https://www.redalyc.org/articulo.oa?id=42333303 en http://www.redalyc.org/revista.oa?id=423 Veterinaria México application/pdf Universidad Nacional Autónoma de México Veterinaria México (México) Num.3 Vol.33 |
| format | Artículo científico |
| id | redalyc_42333303 |
| institution | Redalyc |
| language | en |
| publishDate | 2002 |
| publisher | Universidad Nacional Autónoma de México |
| spellingShingle | Eficacia comparativa de un fasciolicida experimental, triclabendazol y closantel en bovinos infectados en forma natural con Fasciola hepatica Pedro Ochoa Galván Multidisciplinaria (Ciencias Naturales y Exactas) CATTLE CHEMOTHERAPY FASCIOLICIDES FASCIOLAHEPATICA Eficacia comparativa de un fasciolicida experimental, triclabendazol y closantel en bovinos infectados en forma natural con Fasciola hepatica Pedro Ochoa Galván Natividad Montenegro Cristino Yolanda Vera Montenegro Rafael Castillo Bocanegra Alicia Hernández Campos Froylán Ibarra Velarde Multidisciplinaria (Ciencias Naturales y Exactas) CATTLE CHEMOTHERAPY FASCIOLICIDES FASCIOLAHEPATICA The aim of the present study was to determine the efficacy of 5-chloro-2-methylthio-6-(1-naphthyloxy)-ihbenzimidazolecalled compound alfa, which was compared with two commercial fascioliscides through thepercentage of F. hepatica egg-reduction in naturally infected cattle. Forty Holstein-Friesian adult cows, previouslydetermined as positive to fluke eggs by the sedimentation test, were used. They were divided in 4 groups (G) of10 animals each, and were treated with the corresponding dose on day cero. G1 was treated with compound alfaat 12 mg/kg/per os; G2 with triclabendazole at 12 mg/kg/per os; G3 with closantel at 3.5 mg/kg subcutaneously, andG4 remained as the non-treated control. All animals were sampled for feces to carry out coprological examinationson days 15, 8, 0, 7, 14, 21, 28, 60 and 90. Efficacy was assessed on the reduction of egg output on days 14 and 21after the treatment with respect to the control group. Results showed an efficacy of 90.1% and 85.3% for compoundalfa, 91.5% and 96.5% for triclabendazole and 82.1% and 92.1% for closantel. Additional parameters such aspercentage of prevalence, mean number of F. hepatica eggs, standard deviation, extension and intensity effect werealso measured. No statistical differences were found between treatments. It is concluded that all compounds testedconsiderably reduced the percentage of egg excretion, showing an acceptable fasciolicide efficacy. 2002 artículo científico 0301-5092 https://www.redalyc.org/articulo.oa?id=42333303 en http://www.redalyc.org/revista.oa?id=423 Veterinaria México application/pdf Universidad Nacional Autónoma de México Veterinaria México (México) Num.3 Vol.33 |
| title | Eficacia comparativa de un fasciolicida experimental, triclabendazol y closantel en bovinos infectados en forma natural con Fasciola hepatica |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) CATTLE CHEMOTHERAPY FASCIOLICIDES FASCIOLAHEPATICA |
| url | https://www.redalyc.org/articulo.oa?id=42333303 |