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| Natura: | Artículo científico |
| Lingua: | en |
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Universidad Nacional Autónoma de México
2003
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| Accesso online: | https://www.redalyc.org/articulo.oa?id=42334306 |
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Sommario:
- Sobrevivencia de Mycobacterium bovis en macrófagos de bovinos naturalmente resistentes y susceptibles a patógenos intracelulares José A. Gutiérrez Pabello L. Garry Adams Multidisciplinaria (Ciencias Naturales y Exactas) NATURAL RESISTANCE BOVINE MACROPHAGES MYCOBACTERIUM BOVIS Peripheral blood monocyte-derived macrophages from genetically resistant and susceptible cattle tointracellular parasites were evaluated for their ability to control the intracellular growth of virulent M.bovis. Bactericidal assays using a 10:1 multiplicity of infection were performed to study bacterialphagocytosis and bacterial multiplication at 0 and 24 h post-inoculation. The rate of bacterial phagocytosiswas 1.4 ± 0.17 and 2.1 ± 0.54 bacteria/macrophage, whereas bacterial multiplication was 165% and263.7% in macrophages from resistant and susceptible cattle respectively. These results confirm thatmacrophages from resistant and susceptible cattle differ significantly (P<0.01) in controlling intracellularmultiplication of virulent M. bovis. 2003 otro 0301-5092 https://www.redalyc.org/articulo.oa?id=42334306 en http://www.redalyc.org/revista.oa?id=423 Veterinaria México application/pdf Universidad Nacional Autónoma de México Veterinaria México (México) Num.3 Vol.34