Detection of mammary adenocarcinoma metastases in a cat through 99mTc-thymine scintigraphy

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Main Author: Paulo S. Castelo Branco
Format: Artículo científico
Language:en
Published: Universidad Nacional Autónoma de México 2020
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author Paulo S. Castelo Branco
author_facet Paulo S. Castelo Branco
contents Detection of mammary adenocarcinoma metastases in a cat through 99mTc-thymine scintigraphy Paulo S. Castelo Branco Gabriel Gutfilen-Schlesinger Priscila Sena Guile Gutfilen-Schlesinger Sergio A. L. Souza Bianca Gutfilen Multidisciplinaria (Ciencias Naturales y Exactas) 99mTc Cancer thymine Scintigraphy Veterinary care Mammary adenocarcinomas with metastases are more common in dogs than in cats. Their incidence is 1 in every 4,000 cats. In routine veterinary practice, laboratory exams for diagnosis of these neoplasms are nonspecific and scarcely used. Even though invasive procedure, biopsy, and histopathological findings are the gold standards that define the clinical approach, the clinical evaluation, and image assessment lead the way to the proper treatment, especially when surgical intervention is a possibility. This study describes the clinical signs, histopathological aspects, radiological and scintigraphic findings of a cat with mammary adenocarcinoma and metastases evaluated one hour after intravenous administration of 99mTc-thymine. Our focus was not to discuss the pathological aspects of the disease but the Nuclear Medicine role in metastases detection. Metastases, when lesser than 4mm, could go unnoticed by radiological exams, whereas scintigraphy may detect them. Using 99mTc-thymine scintigraphy, we successfully detected unsuspected metastases in the lungs, liver, and right kidney. Early diagnosis is the key to a better rate of survival due to the given treatment and prognostic. Hence, we strongly recommend the use of 99mTc-thymine scintigraphy as a complementary tool for breast cancer diagnosis in veterinary care. 2020 artículo científico 0301-5092 https://www.redalyc.org/articulo.oa?id=42371734002 https://www.redalyc.org/journal/423/42371734002/ https://www.redalyc.org/journal/423/42371734002/html/ https://www.redalyc.org/journal/423/42371734002/42371734002.epub https://www.redalyc.org/journal/423/42371734002/movil 10.22201/fmvz.24486760e.2020.2.718 en http://www.redalyc.org/revista.oa?id=423 Veterinaria México application/pdf Universidad Nacional Autónoma de México Veterinaria México (México) Num.2 Vol.7
format Artículo científico
id redalyc_42371734002
institution Redalyc
language en
publishDate 2020
publisher Universidad Nacional Autónoma de México
spellingShingle Detection of mammary adenocarcinoma metastases in a cat through 99mTc-thymine scintigraphy
Paulo S. Castelo Branco
Multidisciplinaria (Ciencias Naturales y Exactas)
99mTc
Cancer
thymine
Scintigraphy
Veterinary care
Detection of mammary adenocarcinoma metastases in a cat through 99mTc-thymine scintigraphy Paulo S. Castelo Branco Gabriel Gutfilen-Schlesinger Priscila Sena Guile Gutfilen-Schlesinger Sergio A. L. Souza Bianca Gutfilen Multidisciplinaria (Ciencias Naturales y Exactas) 99mTc Cancer thymine Scintigraphy Veterinary care Mammary adenocarcinomas with metastases are more common in dogs than in cats. Their incidence is 1 in every 4,000 cats. In routine veterinary practice, laboratory exams for diagnosis of these neoplasms are nonspecific and scarcely used. Even though invasive procedure, biopsy, and histopathological findings are the gold standards that define the clinical approach, the clinical evaluation, and image assessment lead the way to the proper treatment, especially when surgical intervention is a possibility. This study describes the clinical signs, histopathological aspects, radiological and scintigraphic findings of a cat with mammary adenocarcinoma and metastases evaluated one hour after intravenous administration of 99mTc-thymine. Our focus was not to discuss the pathological aspects of the disease but the Nuclear Medicine role in metastases detection. Metastases, when lesser than 4mm, could go unnoticed by radiological exams, whereas scintigraphy may detect them. Using 99mTc-thymine scintigraphy, we successfully detected unsuspected metastases in the lungs, liver, and right kidney. Early diagnosis is the key to a better rate of survival due to the given treatment and prognostic. Hence, we strongly recommend the use of 99mTc-thymine scintigraphy as a complementary tool for breast cancer diagnosis in veterinary care. 2020 artículo científico 0301-5092 https://www.redalyc.org/articulo.oa?id=42371734002 https://www.redalyc.org/journal/423/42371734002/ https://www.redalyc.org/journal/423/42371734002/html/ https://www.redalyc.org/journal/423/42371734002/42371734002.epub https://www.redalyc.org/journal/423/42371734002/movil 10.22201/fmvz.24486760e.2020.2.718 en http://www.redalyc.org/revista.oa?id=423 Veterinaria México application/pdf Universidad Nacional Autónoma de México Veterinaria México (México) Num.2 Vol.7
title Detection of mammary adenocarcinoma metastases in a cat through 99mTc-thymine scintigraphy
topic Multidisciplinaria (Ciencias Naturales y Exactas)
99mTc
Cancer
thymine
Scintigraphy
Veterinary care
url https://www.redalyc.org/articulo.oa?id=42371734002
https://www.redalyc.org/journal/423/42371734002/
https://www.redalyc.org/journal/423/42371734002/html/
https://www.redalyc.org/journal/423/42371734002/42371734002.epub
https://www.redalyc.org/journal/423/42371734002/movil