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| Main Author: | |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Universidad Nacional Autónoma de México
2019
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| Subjects: | |
| Online Access: | https://www.redalyc.org/articulo.oa?id=42371815003 https://www.redalyc.org/journal/423/42371815003/ https://www.redalyc.org/journal/423/42371815003/html/ https://www.redalyc.org/journal/423/42371815003/42371815003.epub https://www.redalyc.org/journal/423/42371815003/movil |
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Table of Contents:
- Anesthetic evaluation of a novel phospholipid-free 1% propofol microemulsion formulation in dogs Itzcoatl Aquino Eduardo Gutiérrez-Blanco Luis Ocampo Lilia Gutiérrez María J. Bernad-Bernad Héctor Sumano Multidisciplinaria (Ciencias Naturales y Exactas) Dog free Propofol Anesthesia Phospholipid A novel four-week stable experimental formulation of propofol lacking phospholipids (PMICRO) was assessed as an anesthetic agent in dogs and compared to the customary preparation of propofol that contains phospholipids (PMACRO). Forty healthy mixed-breed dogs were included in this study and randomly assigned (blocking by sex and age), to receive 5 mg/kg of one of these two pharmaceutical propofol preparations, by intravenous injection. Basal and post anesthetic blood biochemical parameters were measured. Also, cardiovascular and respiratory rates were recorded. Onset, duration and recovery from anesthesia, were documented as well. Overall, IV administration of PMICRO induces a short duration anesthesia with rapid recovery in a similar manner to anesthesia achieved with the customary propofol preparation (PMACRO). Because PMICRO lacks phospholipids, it may allow a longer storage time, decreasing the likeliness of accidental administration of contaminated propofol. 2019 artículo científico 0301-5092 https://www.redalyc.org/articulo.oa?id=42371815003 https://www.redalyc.org/journal/423/42371815003/ https://www.redalyc.org/journal/423/42371815003/html/ https://www.redalyc.org/journal/423/42371815003/42371815003.epub https://www.redalyc.org/journal/423/42371815003/movil 10.22201/fmvz.24486760e.2019.3.654 en http://www.redalyc.org/revista.oa?id=423 Veterinaria México application/pdf Universidad Nacional Autónoma de México Veterinaria México (México) Num.3 Vol.6