Evaluation of the anti-Newcastle disease vaccine serum on dogs with canine distemper
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| Natura: | Artículo científico |
| Lingua: | en |
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Universidad Nacional Autónoma de México
2022
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| _version_ | 1876447353065439232 |
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| author | Mohammad Arbabi |
| author_facet | Mohammad Arbabi |
| contents | Evaluation of the anti-Newcastle disease vaccine serum on dogs with canine distemper Mohammad Arbabi Ali Asghar Sarchahi Hadi Mohebalian Multidisciplinaria (Ciencias Naturales y Exactas) RT Dog PCR anti distemper Distemper is a contagious, highly lethal, and almost incurable viral disease in dogs and other terrestrial carnivores. This study evaluated a new distemper treatment for dogs. Two healthy male dogs of mixed breed were prepared. A 1 000-dose vial of Newcastle disease vaccine was then diluted with 6 mL normal saline and 3 mL of it was injected into the cephalic vein of each dog, collecting 20 % of the blood volume 11 h later. Blood sera were separated and used as anti-Newcastle disease vaccine serum (ANDVS) to treat dogs suspected of having canine distemper. Dogs with confirmed distemper were grouped into the following seven treatment groups: 1- ANDVS; 2- ANDVS + Cotrimoxazole; 3- ANDVS + Penicillin-Gentamicin; 4- ANDVS + Cefazolin-Amikacin; 5-Cotrimoxa- zole; 6- Penicillin-Gentamycin; 7- Cefazolin-Amikacin. Then the fatality rate of dogs, association between distemper and sex, breed, age, and effects of distemper on hematological factors and vital signs were evaluated. The recovery rates in the ANDVS+ Cotrimoxazole and the ANDVS+ Cefazolin-Amikacin groups were higher than those in the ANDVS group (P < 0.05). Fatality rate was significantly different in distemper-positive and distemper-negative dogs. It is concluded that although ANDVS alone has no effect on the treatment of distemper, it can increase the recovery rate when combined with cotrimoxa- zole or cefazolin + amikacin as compared with the sole use of these antibiotics. 2022 artículo científico 0301-5092 https://www.redalyc.org/articulo.oa?id=42375500020 https://www.redalyc.org/journal/423/42375500020/ https://www.redalyc.org/journal/423/42375500020/html/ https://www.redalyc.org/journal/423/42375500020/42375500020.epub https://www.redalyc.org/journal/423/42375500020/movil https://doi.org/10.22201/fmvz.24486760e.2022.1044 en http://www.redalyc.org/revista.oa?id=423 Veterinaria México application/pdf Universidad Nacional Autónoma de México Veterinaria México (México) Vol.9 |
| format | Artículo científico |
| id | redalyc_42375500020 |
| institution | Redalyc |
| language | en |
| publishDate | 2022 |
| publisher | Universidad Nacional Autónoma de México |
| spellingShingle | Evaluation of the anti-Newcastle disease vaccine serum on dogs with canine distemper Mohammad Arbabi Multidisciplinaria (Ciencias Naturales y Exactas) RT Dog PCR anti distemper Evaluation of the anti-Newcastle disease vaccine serum on dogs with canine distemper Mohammad Arbabi Ali Asghar Sarchahi Hadi Mohebalian Multidisciplinaria (Ciencias Naturales y Exactas) RT Dog PCR anti distemper Distemper is a contagious, highly lethal, and almost incurable viral disease in dogs and other terrestrial carnivores. This study evaluated a new distemper treatment for dogs. Two healthy male dogs of mixed breed were prepared. A 1 000-dose vial of Newcastle disease vaccine was then diluted with 6 mL normal saline and 3 mL of it was injected into the cephalic vein of each dog, collecting 20 % of the blood volume 11 h later. Blood sera were separated and used as anti-Newcastle disease vaccine serum (ANDVS) to treat dogs suspected of having canine distemper. Dogs with confirmed distemper were grouped into the following seven treatment groups: 1- ANDVS; 2- ANDVS + Cotrimoxazole; 3- ANDVS + Penicillin-Gentamicin; 4- ANDVS + Cefazolin-Amikacin; 5-Cotrimoxa- zole; 6- Penicillin-Gentamycin; 7- Cefazolin-Amikacin. Then the fatality rate of dogs, association between distemper and sex, breed, age, and effects of distemper on hematological factors and vital signs were evaluated. The recovery rates in the ANDVS+ Cotrimoxazole and the ANDVS+ Cefazolin-Amikacin groups were higher than those in the ANDVS group (P < 0.05). Fatality rate was significantly different in distemper-positive and distemper-negative dogs. It is concluded that although ANDVS alone has no effect on the treatment of distemper, it can increase the recovery rate when combined with cotrimoxa- zole or cefazolin + amikacin as compared with the sole use of these antibiotics. 2022 artículo científico 0301-5092 https://www.redalyc.org/articulo.oa?id=42375500020 https://www.redalyc.org/journal/423/42375500020/ https://www.redalyc.org/journal/423/42375500020/html/ https://www.redalyc.org/journal/423/42375500020/42375500020.epub https://www.redalyc.org/journal/423/42375500020/movil https://doi.org/10.22201/fmvz.24486760e.2022.1044 en http://www.redalyc.org/revista.oa?id=423 Veterinaria México application/pdf Universidad Nacional Autónoma de México Veterinaria México (México) Vol.9 |
| title | Evaluation of the anti-Newcastle disease vaccine serum on dogs with canine distemper |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) RT Dog PCR anti distemper |
| url | https://www.redalyc.org/articulo.oa?id=42375500020 https://www.redalyc.org/journal/423/42375500020/ https://www.redalyc.org/journal/423/42375500020/html/ https://www.redalyc.org/journal/423/42375500020/42375500020.epub https://www.redalyc.org/journal/423/42375500020/movil https://doi.org/10.22201/fmvz.24486760e.2022.1044 |