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| Format: | Artículo científico |
| Sprache: | es |
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Universidad Mayor de San Andrés
2009
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| Online-Zugang: | https://www.redalyc.org/articulo.oa?id=426339672001 |
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| _version_ | 1866592994357936128 |
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| author | Joahan Rojas U. |
| author_facet | Joahan Rojas U. |
| contents | ACTIVIDAD LEISHMANICIDA DE PLANTAS MEDICINALESDE LA AMAZONIA PERUANA Joahan Rojas U. Johann R. Satalaya A. Maritza Grandez R. Luis Vilchez A. Elsa Rengifo S. Efrain Salamanca C Ninoska Flores Q Alberto Giménez T. Juan Antonio Ávila I. Grace Ruiz P. Química In this study the eight medicinal plants from the Peruvian Amazon were evaluated searching their parasiticide activity in vitro: Ampelozizyphus amazonicus, Andira inermes, Bellusia pentamera, Couma macrocarpa, Croton lechleri, Unonopsis spectabilis, Urena lobat and, Xilopia parviflor. The study was performed using different species of promastigotes from Leishmania: L. amazonensis (IFLA/BR/75/PH8), L. braziliensis(MHOM/BR/75/M2903) and L. donovani (MHOM/74/PP75) . The assays were developed by count trough an optical method in a Neubauer camera and fractions that were active have been evaluated with the colorimetric the method using XTT. The organic CH2Cl2 extract from Unonopsis spectabilis was the more active with an IC50 65.3, 54.2 and 24.5 mg/mL vs. L. amazonensis (IFLA/BR/75/PH8), L. braziliensis (MHOM/BR/75/M2903) and L. donovani (MHOM/74/PP75) from the optical method respectively. In order to determine the leishmanicide activity of the organic fraction the colorimetric XTT method was used against L. braziliensis (MHOM/BR/75/M2903) and L. amazonensis (MHOM/BR/76/LTB-012). The results showed values of IC50 between 10.6 mg/mL and 11.8 mg/mL respectively. 2009 artículo científico 0250-5460 https://www.redalyc.org/articulo.oa?id=426339672001 es http://www.redalyc.org/revista.oa?id=4263 Revista Boliviana de Química application/pdf Universidad Mayor de San Andrés Revista Boliviana de Química (Estado Plurinacional de Bolivia) Num.2 Vol.26 |
| format | Artículo científico |
| id | redalyc_426339672001 |
| language | es |
| publishDate | 2009 |
| publisher | Universidad Mayor de San Andrés |
| spellingShingle | ACTIVIDAD LEISHMANICIDA DE PLANTAS MEDICINALESDE LA AMAZONIA PERUANA Joahan Rojas U. Química ACTIVIDAD LEISHMANICIDA DE PLANTAS MEDICINALESDE LA AMAZONIA PERUANA Joahan Rojas U. Johann R. Satalaya A. Maritza Grandez R. Luis Vilchez A. Elsa Rengifo S. Efrain Salamanca C Ninoska Flores Q Alberto Giménez T. Juan Antonio Ávila I. Grace Ruiz P. Química In this study the eight medicinal plants from the Peruvian Amazon were evaluated searching their parasiticide activity in vitro: Ampelozizyphus amazonicus, Andira inermes, Bellusia pentamera, Couma macrocarpa, Croton lechleri, Unonopsis spectabilis, Urena lobat and, Xilopia parviflor. The study was performed using different species of promastigotes from Leishmania: L. amazonensis (IFLA/BR/75/PH8), L. braziliensis(MHOM/BR/75/M2903) and L. donovani (MHOM/74/PP75) . The assays were developed by count trough an optical method in a Neubauer camera and fractions that were active have been evaluated with the colorimetric the method using XTT. The organic CH2Cl2 extract from Unonopsis spectabilis was the more active with an IC50 65.3, 54.2 and 24.5 mg/mL vs. L. amazonensis (IFLA/BR/75/PH8), L. braziliensis (MHOM/BR/75/M2903) and L. donovani (MHOM/74/PP75) from the optical method respectively. In order to determine the leishmanicide activity of the organic fraction the colorimetric XTT method was used against L. braziliensis (MHOM/BR/75/M2903) and L. amazonensis (MHOM/BR/76/LTB-012). The results showed values of IC50 between 10.6 mg/mL and 11.8 mg/mL respectively. 2009 artículo científico 0250-5460 https://www.redalyc.org/articulo.oa?id=426339672001 es http://www.redalyc.org/revista.oa?id=4263 Revista Boliviana de Química application/pdf Universidad Mayor de San Andrés Revista Boliviana de Química (Estado Plurinacional de Bolivia) Num.2 Vol.26 |
| title | ACTIVIDAD LEISHMANICIDA DE PLANTAS MEDICINALESDE LA AMAZONIA PERUANA |
| topic | Química |
| url | https://www.redalyc.org/articulo.oa?id=426339672001 |