DETERMINATION OF THE PHENOLIC CONTENTS, AND EVALUATION OF THE ANTITYROSINASE ACTIVITY, AND THE ANTIOXIDANT INDEXES OF FOUR BOLIVIAN QUINOA VARIETIES
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Universidad Mayor de San Andrés
2020
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| _version_ | 1876434991682945024 |
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| author | Alejandra Navia |
| author_facet | Alejandra Navia |
| contents | DETERMINATION OF THE PHENOLIC CONTENTS, AND EVALUATION OF THE ANTITYROSINASE ACTIVITY, AND THE ANTIOXIDANT INDEXES OF FOUR BOLIVIAN QUINOA VARIETIES Alejandra Navia Peggy Ormachea Lily Salcedo Maribel Lozano Santiago Tarqui Yonny Flores Giovanna R. Almanza Química Quinoa Antioxidant Mauritianin Antityrosinase Chenopodium quinoa Four varieties of Bolivian quinoa (QJG Quinoa Jacha Grano, QRB Quinoa Real Blanca, QRN Quinoa Real Negra and QRR Quinoa Real Roja) have been studied in order to valorize them through the establishment of the phenolic contents and consequently by their antioxidant indexes. In addition, and in this pathway, the antityrosinase activity of the four varieties was measured. One important quinoa-endemic glycosylated flavonoid, mauritianin . (Kaempferol-3-O-(2,6-di-O-α-ramnopyranosyl-β-galactopyranoside) was isolated, and identified by cromatographic and spectroscopic methods and it was quantified. The four quinoa samples were treated by means of solid-liquid extractions with hydro-alcoholic 8:2 solvents. Quantifications and evaluations were done in the samples of the four varieties of quinoa and in phenolic rich fractions from the extract of QJG, and in compound ., coming from the QJG extract. In a series of in vitro tests, antioxidant indexes, by means of the total phenolic content and ABTS methods, and antityrosinase activities, by using the fungal tyrosinase method, of phenolic rich fractions and of the pure compound . were evaluated, . showed an important antityrosinase activity (74.73% I at 1.67 mg/mL) and antioxidant (826.68 mg GAE/g and 1141.38 µM Trolox/g), as well as the phenolic rich fraction from the extract of QJG named as EEW-1 that showed 69.89% I of the enzyme tyrosinase and significant antioxidant activity (246.08 mg GAE/g and 569.21 uM trolox/g), suggesting that these products could have a potential application in dermatology, cosmetics and food processing. 2020 artículo científico 0250-5460 https://www.redalyc.org/articulo.oa?id=426363282002 https://www.redalyc.org/journal/4263/426363282002/ https://www.redalyc.org/journal/4263/426363282002/html/ https://www.redalyc.org/journal/4263/426363282002/426363282002.epub https://www.redalyc.org/journal/4263/426363282002/movil en http://www.redalyc.org/revista.oa?id=4263 Revista Boliviana de Química application/pdf Universidad Mayor de San Andrés Revista Boliviana de Química (Estado Plurinacional de Bolivia) Num.1 Vol.37 |
| format | Artículo científico |
| id | redalyc_426363282002 |
| institution | Redalyc |
| language | en |
| publishDate | 2020 |
| publisher | Universidad Mayor de San Andrés |
| spellingShingle | DETERMINATION OF THE PHENOLIC CONTENTS, AND EVALUATION OF THE ANTITYROSINASE ACTIVITY, AND THE ANTIOXIDANT INDEXES OF FOUR BOLIVIAN QUINOA VARIETIES Alejandra Navia Química Quinoa Antioxidant Mauritianin Antityrosinase Chenopodium quinoa DETERMINATION OF THE PHENOLIC CONTENTS, AND EVALUATION OF THE ANTITYROSINASE ACTIVITY, AND THE ANTIOXIDANT INDEXES OF FOUR BOLIVIAN QUINOA VARIETIES Alejandra Navia Peggy Ormachea Lily Salcedo Maribel Lozano Santiago Tarqui Yonny Flores Giovanna R. Almanza Química Quinoa Antioxidant Mauritianin Antityrosinase Chenopodium quinoa Four varieties of Bolivian quinoa (QJG Quinoa Jacha Grano, QRB Quinoa Real Blanca, QRN Quinoa Real Negra and QRR Quinoa Real Roja) have been studied in order to valorize them through the establishment of the phenolic contents and consequently by their antioxidant indexes. In addition, and in this pathway, the antityrosinase activity of the four varieties was measured. One important quinoa-endemic glycosylated flavonoid, mauritianin . (Kaempferol-3-O-(2,6-di-O-α-ramnopyranosyl-β-galactopyranoside) was isolated, and identified by cromatographic and spectroscopic methods and it was quantified. The four quinoa samples were treated by means of solid-liquid extractions with hydro-alcoholic 8:2 solvents. Quantifications and evaluations were done in the samples of the four varieties of quinoa and in phenolic rich fractions from the extract of QJG, and in compound ., coming from the QJG extract. In a series of in vitro tests, antioxidant indexes, by means of the total phenolic content and ABTS methods, and antityrosinase activities, by using the fungal tyrosinase method, of phenolic rich fractions and of the pure compound . were evaluated, . showed an important antityrosinase activity (74.73% I at 1.67 mg/mL) and antioxidant (826.68 mg GAE/g and 1141.38 µM Trolox/g), as well as the phenolic rich fraction from the extract of QJG named as EEW-1 that showed 69.89% I of the enzyme tyrosinase and significant antioxidant activity (246.08 mg GAE/g and 569.21 uM trolox/g), suggesting that these products could have a potential application in dermatology, cosmetics and food processing. 2020 artículo científico 0250-5460 https://www.redalyc.org/articulo.oa?id=426363282002 https://www.redalyc.org/journal/4263/426363282002/ https://www.redalyc.org/journal/4263/426363282002/html/ https://www.redalyc.org/journal/4263/426363282002/426363282002.epub https://www.redalyc.org/journal/4263/426363282002/movil en http://www.redalyc.org/revista.oa?id=4263 Revista Boliviana de Química application/pdf Universidad Mayor de San Andrés Revista Boliviana de Química (Estado Plurinacional de Bolivia) Num.1 Vol.37 |
| title | DETERMINATION OF THE PHENOLIC CONTENTS, AND EVALUATION OF THE ANTITYROSINASE ACTIVITY, AND THE ANTIOXIDANT INDEXES OF FOUR BOLIVIAN QUINOA VARIETIES |
| topic | Química Quinoa Antioxidant Mauritianin Antityrosinase Chenopodium quinoa |
| url | https://www.redalyc.org/articulo.oa?id=426363282002 https://www.redalyc.org/journal/4263/426363282002/ https://www.redalyc.org/journal/4263/426363282002/html/ https://www.redalyc.org/journal/4263/426363282002/426363282002.epub https://www.redalyc.org/journal/4263/426363282002/movil |