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| Format: | Artículo científico |
| Sprache: | en |
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Universidade Estadual Paulista Júlio de Mesquita Filho
2008
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| Online-Zugang: | https://www.redalyc.org/articulo.oa?id=42915808008 |
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Inhaltsangabe:
- Anacardic acid derivatives from Brazilian propolis and their antibacterial activity M. S. S. Silva S. G. De Lima E. H. Oliveira J. A. D. Lopes M. H. Chaves F. A. M. Reis A. M. G. L. Citó Química Triterpenoids Anacardic acid Alkylthiolation Brazilian propolis Antibacterial activity Propolis is a sticky, gummy, resinous substance collected by honeybees (Apis mellifera L.) from various plant sources, which has excellent medicinal properties. This paper describes the isolation and identification of triterpenoids and anacardic acid derivatives from Brazilian propolis and their antibacterial activity. Their structures were elucidated by ¹H and 13C NMR, including uni- and bidimensional techniques; in addition, comparisons were made with data from academic literature. These compounds were identified as: cardanols (1a + 1b), cardols (2a + 2b), monoene anacardic acid (3), a-amirine (4), b-amirine (5), cycloartenol (6), 24-methylene-cycloartenol (7) and lupeol (8). The determination of the position of the double bond after a reaction with Dimethyl disulfide (DMDS) is described for the phenol derivatives. The ethanolic extract was tested in vitro for antimicrobial activity by using the disc diffusion method and it showed significant results against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Shigella spp. 2008 artículo científico 0100-4670 https://www.redalyc.org/articulo.oa?id=42915808008 en http://www.redalyc.org/revista.oa?id=429 Eclética Química application/pdf Universidade Estadual Paulista Júlio de Mesquita Filho Eclética Química (Brasil) Num.3 Vol.33