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| Format: | Artículo científico |
| Language: | en |
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Universidade Estadual Paulista Júlio de Mesquita Filho
2011
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| Online Access: | https://www.redalyc.org/articulo.oa?id=42938348002 |
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Table of Contents:
- EFFECT ON THE INHIBITORY ACTIVITY OF POTENTIAL MICROBES ON THE COMPLEXATION OF METHYL ANTHRANILATE DERIVED HYDRAZIDE WITH CU, NI AND ZN(II) METAL IONS Saeed-Ur Rehman Mazhar-Ul Islam Muhammad Ikram Sadia Rehman Syed Muhammad Shah Kamran Mahdi Farhat Ullah Química bioassay studies Aminobenzohydrazine coordination compounds The present report is concerned with the synthesis and coordination compounds of 2-amino-(N-aminobezoyl) benzohydrazide[ABH]. The ligand was charcterized by proton NMR, mass spectrometry, elemental and infrared studies. The ligand has got –NH2 moeity which is capable of chelation. Therefore complexes of Ni, Cu, and Zn were prepared. These complexes were characterized by elemental, infrared, thermal, conductance, and magnetic susceptibility studies. Infrared spectra shows that the ligand form complexes through –NH2 moeity, while the elemental studies suggest M(ABH)X2 composition of the coordination compounds. Knowing about the importance of -N-N- linkage in the biologically active compounds, the synthesized complexes were studied for their biological activities against Gram Negative bacteria which include E. coli, Salmonella typhi, Enterobacter aerogenes, Proteus vulgaris and Pseudomonas aeruginosa, selected Gram Positive bacterial strain is Staph aureus and Fungus like Candida albican. These activities show that the hydrazide containing metal complexes become more potentially resistive to the microbial activities as compared to the sole ligand. 2011 artículo científico 0100-4670 https://www.redalyc.org/articulo.oa?id=42938348002 en http://www.redalyc.org/revista.oa?id=429 Eclética Química application/pdf Universidade Estadual Paulista Júlio de Mesquita Filho Eclética Química (Brasil) Num.3 Vol.36