Fabrication of chitosan/bioactive glass composite scaffolds for medical applications

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Autor principal: Diana Marcela Escobar-Sierra
Formato: Artículo científico
Lenguaje:en
Publicado: Universidad de Antioquia 2016
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author Diana Marcela Escobar-Sierra
author_facet Diana Marcela Escobar-Sierra
contents Fabrication of chitosan/bioactive glass composite scaffolds for medical applications Diana Marcela Escobar-Sierra Johnnatan Stiven Posada-Carvajal Diego León Atehortúa-Soto Ingeniería chitosan scaffolds Bioactive glass tissue engineering In the current study, a bioactive glass (BG) powder was prepared by sol-gel technique in the system SiO2 –CaO–P2O5, and both, bioactive glass precursors (BGi) and the powder of bioactive glass (BGp) were used to produce crosslinked chitosan composite scaffolds (CH/BGi and CH/BGp), which were produced by lyophilization. The bioactive glass was analyzed to know its composition, crystallinity and morphology through Raman Spectroscopy (RS), X-Ray Diffraction (XRD) and Scanning Electron Microscopy (SEM), respectively. In addition, compression strength tests were carried out on the resulting composite scaffolds. Experimental results show that the fabricated CH/BG scaffolds might be a promising composite biomaterial for bone tissue engineering, due to the XRD results, showing a pollutant-free biomaterial, and, SEM shows bioactive glass particles homogenously distributed within the chitosan matrix which suggested that the developed composite scaffolds possess the prerequisites for tissue engineering and these can be used for tissue engineering applications. 2016 artículo científico 0120-6230 https://www.redalyc.org/articulo.oa?id=43047073005 en http://www.redalyc.org/revista.oa?id=430 Revista Facultad de Ingeniería Universidad de Antioquia application/pdf Universidad de Antioquia Revista Facultad de Ingeniería Universidad de Antioquia (Colombia) Num.80
format Artículo científico
id redalyc_43047073005
institution Redalyc
language en
publishDate 2016
publisher Universidad de Antioquia
spellingShingle Fabrication of chitosan/bioactive glass composite scaffolds for medical applications
Diana Marcela Escobar-Sierra
Ingeniería
chitosan
scaffolds
Bioactive glass
tissue engineering
Fabrication of chitosan/bioactive glass composite scaffolds for medical applications Diana Marcela Escobar-Sierra Johnnatan Stiven Posada-Carvajal Diego León Atehortúa-Soto Ingeniería chitosan scaffolds Bioactive glass tissue engineering In the current study, a bioactive glass (BG) powder was prepared by sol-gel technique in the system SiO2 –CaO–P2O5, and both, bioactive glass precursors (BGi) and the powder of bioactive glass (BGp) were used to produce crosslinked chitosan composite scaffolds (CH/BGi and CH/BGp), which were produced by lyophilization. The bioactive glass was analyzed to know its composition, crystallinity and morphology through Raman Spectroscopy (RS), X-Ray Diffraction (XRD) and Scanning Electron Microscopy (SEM), respectively. In addition, compression strength tests were carried out on the resulting composite scaffolds. Experimental results show that the fabricated CH/BG scaffolds might be a promising composite biomaterial for bone tissue engineering, due to the XRD results, showing a pollutant-free biomaterial, and, SEM shows bioactive glass particles homogenously distributed within the chitosan matrix which suggested that the developed composite scaffolds possess the prerequisites for tissue engineering and these can be used for tissue engineering applications. 2016 artículo científico 0120-6230 https://www.redalyc.org/articulo.oa?id=43047073005 en http://www.redalyc.org/revista.oa?id=430 Revista Facultad de Ingeniería Universidad de Antioquia application/pdf Universidad de Antioquia Revista Facultad de Ingeniería Universidad de Antioquia (Colombia) Num.80
title Fabrication of chitosan/bioactive glass composite scaffolds for medical applications
topic Ingeniería
chitosan
scaffolds
Bioactive glass
tissue engineering
url https://www.redalyc.org/articulo.oa?id=43047073005