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| Format: | Artículo científico |
| Language: | en |
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Medical Education Cooperation with Cuba
2008
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| Online Access: | https://www.redalyc.org/articulo.oa?id=437542065007 |
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Table of Contents:
- Prevalence of Obesity and its Association with Chronic Kidney Disease, Hypertension and Diabetes Mellitus. Isle of Youth Study (ISYS), Cuba Raúl Herrera Valdés Miguel Almaguer López José Chipi Cabrera Xidix Toirac Cabrera Orquídea Martínez Soto Osvaldo Castellanos Rabanal Jorge Bacallao Gallestey Rosa M. Licourt Pérez Pedro Mulet Pineda Luisa Diéguez Pérez Israel Velásquez Batista María C. Hernández Rivero Walfrido Caballero Odio Pedro Urra González Néstor Rodríguez Triana Medicina CKD obe sity overweight hypertension Introduction Obesity is a social disease constituting a global pan-demic. It is present in 90% of diabetic and 65% of hypertensive pa-tients. It is associated with cardiometabolic syndrome and with dam-aging physiopathological mechanisms, particularly for the vascular system and the kidneys. On Cuba’s Isle of Youth, a community-based epidemiological study of chronic kidney disease (CKD), hypertension (HTN), diabetes mellitus (DM) and cardio-cerebral vascular disease was carried out in total population, including an examination of com-mon risk factors.Objective Based on the Isle of Youth Study (ISYS) data, determine prevalence of obesity and overweight, and their association with CKD, HTN, DM, and shared risk factors for all these conditions in total popu-lation of the Isle of Youth, Cuba.Methods Phase 1:Population diagnosis (November 2004-April 2006): 96.6% of the Isle of Youth’s total population (80,117) was studied, including all ages and both sexes. Information was offered to the public, and written informed consent obtained. Screening was conducted by participant questionnaire including risk factors, physical measurements (weight, height, blood pressure and body mass index), and a single first-morning urine sample to determine the presence of vascular-renal damage markers – proteinuria and hematuria (Combur 10 Test, Roche), and microalbuminuria (Micral Test, Roche). When results were positive, serum creatinine was determined and glomeru-lar filtration rate (GFR) estimated with Modification of Diet in Renal Disease (MDRD) formula for adults and Schwartz formula for children <15 years. Data obtained were analyzed to determine association of participants’ nutritional status with prevalence of chronic kidney dis-ease, hypertension and diabetes mellitus, as well as a set of common risk factors.Results Population <20 years: Obesity prevalence 3.2%; positive urine markers in 56.9% of obese and 8.9% of non-obese participants; positive albuminuria in 38% of obese and 3% of non-obese. Obese participants were found to be hyperfiltrating. DM prevalence was 9.5% in obese and 1.1% in non-obese participants. Population ≥20 years: Overweight, 31.3%; obese, 13.4%. Positive markers in normal-weight, overweight and obese individuals were 18.3%, 21.2% and 32.7%, re-spectively; microalbuminuria values increased with weight. Obese in-dividuals were found to be hyperfiltrating. HTN prevalence in normal-weight, overweight and obese individuals was 18.3%, 31.5%, and 51.0% respectively; DM rates were 2.8%, 5.2% y 11.3%, respectively.Conclusion In Cuba, obesity poses significant risk for vascular and renal damage and should be the focus of increased prevention ef-forts. 2008 artículo científico 1555-7960 https://www.redalyc.org/articulo.oa?id=437542065007 en http://www.redalyc.org/revista.oa?id=4375 MEDICC Review application/pdf Medical Education Cooperation with Cuba MEDICC Review (Estados Unidos de América) Num.2 Vol.10