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| Formato: | Artículo científico |
| Lenguaje: | en |
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Medical Education Cooperation with Cuba
2012
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| Acceso en línea: | https://www.redalyc.org/articulo.oa?id=437542087005 |
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- Hormone Profile of Menopausal Women in Havana Daysi Navarro Alina Acosta Erick Robles Cóssette Díaz Medicina cli Cuba lutein female Hormones INTRODUCTION There is a tendency among women today to delay the age at which they have their fi rst child or subsequent children. This creates a dilemma for couples, since health professionals tend to counsel against pregnancy in women aged ≥40 years without consid-ering their reproductive potential and their ability to and likelihood of conceiving and carrying to term a healthy newborn at little or no risk. OBJECTIVE Assess hypothalamic-pituitary-gonadal axis function in meno-pausal women in Havana, to evaluate relevance to reproductive potential.METHODS A retrospective study was conducted from March 2006 through March 2008 of 230 healthy women aged 40–59 years seen in the Menopause and Osteoporosis Clinic in Havana, Cuba. Chart review yielded data on current age, stage of climacteric and hormone levels expressed in means and standard deviations: serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol and testosterone. Analysis of variance was used for assesment by age group and stage of menopause (eumenorrheic, perimenopausal and postmenopausal), with a p value of <0.05 set as signifi cance level.RESULTS Mean serum hormone levels in eumenorrheic women were: FSH 6.97 IU/L, LH 4.23 IU/L and estradiol 314 pmol/L; in peri-menopausal women: FSH 34.69 IU/L, LH 20.78 IU/L and estradiol 201 pmol/L; and in postmenopausal women: FSH 75.43 IU/L, LH 37.59 IU/L and estradiol 117 pmol/L (p <0.05 for difference between eumenorrheic and postmenopausal women). There was a progres-sive increase in FSH and LH and a decline in estradiol with older age. There was no signifi cant difference in testosterone levels by age or stage of menopause. CONCLUSIONS Menstrual cycle and hormonal levels of the hypo-thalamic-pituitary-gonadal axis should be considered in addition to chronological age when determining reproductive potential in women aged 40–59 years. 2012 artículo científico 1555-7960 https://www.redalyc.org/articulo.oa?id=437542087005 en http://www.redalyc.org/revista.oa?id=4375 MEDICC Review application/pdf Medical Education Cooperation with Cuba MEDICC Review (Estados Unidos de América) Num.2 Vol.14